Evidence map›Paper›PMID 17568824›Full record

ArticleCanadian journal of gastroenterology = Journal canadien de gastroenterologie2007

Management of chronic hepatitis C: consensus guidelines.

Morris Sherman, Stephen Shafran, Kelly Burak, Karen Doucette, Winnie Wong, Nigel Girgrah, Eric Yoshida, Eberhard Renner, Philip Wong, Marc Deschênes

Registry-linked trialOpen access · goldAbstract readConsensus Statement
In one paragraph

Article in Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01095445 (EXtended Therapy in Genotype 3 Infected Patients Who do Not AChieve a Treatment Response at Week 4), which is not on this map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01095445 phase3terminatednot on this mapstarted 2010, after this paper: background citation

EXtended Therapy in Genotype 3 Infected Patients Who do Not AChieve a Treatment Response at Week 4 (RVR) But do Achieve a Complete Early Virologic Response (cEVR)

TypeinterventionalSponsorUniversity Health Network, TorontoRan2010 to 2011Enrolled2ConditionsChronic Hepatitis CArmsPeginterferon alfa-2b (Pegetron) plus ribavirin (Rebetol)
3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it, 141 citations in OpenAlex.

  1. An update on the management of hepatitis C: consensus guidelines from the Canadian Association for the Study of the Liver.Canadian journal of gastroenterology = Journal canadien de gastroenterologie · 2012
    Guideline
  2. Trial
  3. Trial
  4. Article
  5. Characterizing the cascade of care for hepatitis C virus infection among Status First Nations peoples in Ontario: a retrospective cohort study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
  11. Real-world effectiveness of peginterferon α-2b plus ribavirin in a Canadian cohort of treatment-naïve chronic hepatitis C patients with genotypes 2 or 3: results of the PoWer and RediPEN studies.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2016
    Observational
  12. Cost-effectiveness of screening for hepatitis C in Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2015
    Article
  13. Hepatitis C surveillance in Canada.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2014
    Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. The epidemiology of hepatitis C in a Canadian Indigenous population.Canadian journal of gastroenterology = Journal canadien de gastroenterologie · 2013
    Article
  19. Hepatitis C and the surgeon.Canadian journal of surgery. Journal canadien de chirurgie · 2013
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Morris ShermanDepartment of Medicine, University of Toronto, Toronto General Hospital, Toronto, Ontario, Canada. morris.sherman@uhn.on.ca
Stephen Shafran
Kelly Burak
Karen Doucette
Winnie Wong
Nigel Girgrah
Eric Yoshida
Eberhard Renner
Philip Wong
Marc Deschênes
University of Alberta · CAMcGill University · CAUniversity of Toronto · CAUniversity of British Columbia · CAUniversity of Calgary · CAUniversity of Manitoba · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Since the last consensus conference on the management of chronic viral hepatitis, a number of studies looking at modifications of the standard course of treatment have been published. These changes have been sufficiently substantive to warrant review to determine whether any changes in the recommended treatment algorithms are needed. A consensus development conference was held in January 2007, and the present document highlights the results of the presentations and discussion about these issues. It reviews the epidemiology of hepatitis C in Canada, treatment of acute hepatitis C and new algorithms in chronic hepatitis C, including retreatment of previous treatment failures. In addition, sections on management of hepatitis C in special populations have been updated. There is also a section on the use of hematopoietic growth factors to help manage patients on therapy. The document should be read in conjunction with the previous document to identify changes. Some recommendations made in the previous document remain and are not discussed here.

Indexed as

Practice Guidelines as TopicAntiviral AgentsCanadaHepatitis CHumansAntiviral Agents

Identifiers

PMID17568824
PMCPMC2794457
OpenAlexW2129683974

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.