ReviewCanadian journal of surgery. Journal canadien de chirurgie2007
An approach to transfusion and hemorrhage in trauma: current perspectives on restrictive transfusion strategies.
Review in Canadian journal of surgery. Journal canadien de chirurgie, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Leukoreduction for the prevention of adverse reactions from allogeneic blood transfusion.The Cochrane database of systematic reviews · 2015Pooled it
- Prolonged storage of packed red blood cells for blood transfusion.The Cochrane database of systematic reviews · 2015Pooled it
- Appropriateness of Allogeneic Red Blood Cell Transfusions in Non-Bleeding Patients in a Large Teaching Hospital: A Retrospective Study.Journal of clinical medicine · 2023Article
- The epidemiology of overtransfusion of red cells in trauma resuscitation patients in the context of a mature massive transfusion protocol.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Endoscopic Combined Intrarenal Surgery Versus Percutaneous Nephrolithotomy for Complex Renal Stones: A Systematic Review and Meta-Analysis.Journal of personalized medicine · 2022Review
- Overtransfusion of packed red blood cells during massive transfusion activation: a potential quality metric for trauma resuscitation.Trauma surgery & acute care open · 2022Article
- Hemoglobin-based Oxygen Carriers: Current State-of-the-art and Novel Molecules.Shock (Augusta, Ga.) · 2019Review
- Crystalloid resuscitation in trauma patients: deleterious effect of 5L or more in the first 24h.BMC surgery · 2018Article
- Comparison of the impact of applications of Targeted Transfusion Protocol and Massive Transfusion Protocol in trauma patients.Korean journal of anesthesiology · 2017Article
- Hemodynamic Changes Following Routine Fluid Resuscitation in Patients With Blunt Trauma.Trauma monthly · 2016Article
- Analysis of Risk Factors for Gunshot Wound Infection in a Nigerian Civilian Trauma Setting.World journal of surgery · 2016Article
- Association between frequency of blood tests and mortality rate in patients undergoing massive blood transfusion: a multicenter study in five regions of China.International journal of clinical and experimental medicine · 2015Article
- Red blood cell transfusion and mortality in trauma patients: risk-stratified analysis of an observational study.PLoS medicine · 2014Observational
- Effects of Intravenous Fluid Therapy on Clinical and Biochemical Parameters of Trauma Patients.Emergency (Tehran, Iran) · 2014Article
- Tissue ischemia microdialysis assessments following severe traumatic haemorrhagic shock: lactate/pyruvate ratio as a new resuscitation end point?BMC anesthesiology · 2014Observational
- Changes in the outcomes of severe trauma patients from 15-year experience in a Western European trauma ICU of Emilia Romagna region (1996-2010). A population cross-sectional survey study.Langenbeck's archives of surgery · 2014Article
- Evolution of the role of army transfusion services in the management of trauma patients and battle casualties with massive hemorrhage.Medical journal, Armed Forces India · 2012Review
- Effect of damage control surgery on major abdominal vascular trauma.The Journal of surgical research · 2012Article
- Protease activity increases in plasma, peritoneal fluid, and vital organs after hemorrhagic shock in rats.PloS one · 2012Article
- Uncrossmatched blood transfusions for trauma patients in the emergency department: incidence, outcomes and recommendations.Canadian journal of surgery. Journal canadien de chirurgie · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hemorrhagic shock is a leading cause of death in trauma patients. Surgical control of bleeding and fluid resuscitation with both crystalloid and blood products remain the mainstay of therapy for injured patients with bleeding. However, there has been a recent re-evaluation of transfusion practice. Both the fear of transmissible disease and the costs of transfusing blood products have led to increasingly restrictive transfusion practices. A small percentage of trauma patients require massive transfusion. These patients are complex and difficult to manage, and clinicians must act quickly to save them. There is little evidence to help guide clinical transfusion decisions in these patients. A rational approach to using blood products requires an understanding of the end points of resuscitation. Resuscitation with fluids and red cells is necessary to improve perfusion and oxygen delivery to tissues. Avoiding overtransfusion is key, however, because transfusion is also associated with significant risks. This trend toward reducing allogenic blood exposure will likely continue. New technologies that have the potential of reducing blood loss and transfusion requirements in trauma patients with massive bleeding are being developed, and similar old technologies are being reapplied.
Indexed as
Identifiers
17568492PMC2384284W1493527754What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.