ArticleThe review of diabetic studies : RDS2007
Genes, diet and type 2 diabetes mellitus: a review.
Article in The review of diabetic studies : RDS, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- Prevalence of intestinal parasitic infections in patients with diabetes: a systematic review and meta-analysis.International health · 2024Pooled it
- Changes of Regulatory T Cells and of Proinflammatory and Immunosuppressive Cytokines in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis.Journal of diabetes research · 2016Pooled it
- Pooled it
- A detailed examination of the worldwide impact of type 2 diabetes linked to dietary risks: insights from the Global Burden of Disease Study (1990-2021).Frontiers in endocrinology · 2026Article
- High-fat diet may increase the risk of insulin resistance by inducing dysbiosis.Metabolism open · 2025Review
- Non high density lipoprotein to high density lipoprotein cholesterol ratio and type 2 diabetes in Middle aged and Elderly Chinese.Scientific reports · 2025Article
- Association between adiponectin single nucleotide polymorphisms and the risk of diabetic polyneuropathy.Scientific reports · 2025Article
- Association of transcription factor 7-like 2 rs12255372 polymorphism with susceptibility of type 2 diabetes mellitus in Bangladeshi population.Molecular genetics and genomics : MGG · 2023Article
- Human Gut Microbiota in Health and Selected Cancers.International journal of molecular sciences · 2021Review
- Manipulation of intestinal microbiome as potential treatment for insulin resistance and type 2 diabetes.European journal of nutrition · 2021Review
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- Roles of ginsenosides in inflammasome activation.Journal of ginseng research · 2019Review
- Temporal Proteomic Analysis of Pancreatic β-Cells in Response to Lipotoxicity and Glucolipotoxicity.Molecular & cellular proteomics : MCP · 2018Article
- The impact of a short-term high-fat diet on mitochondrial respiration, reactive oxygen species production, and dynamics in oxidative and glycolytic skeletal muscles of young rats.Physiological reports · 2018Article
- Shortcuts to a functional adipose tissue: The role of small non-coding RNAs.Redox biology · 2017Review
- Catalase deletion promotes prediabetic phenotype in mice.Free radical biology & medicine · 2017Article
- Myo-inositol inhibits intestinal glucose absorption and promotes muscle glucose uptake: a dual approach study.Journal of physiology and biochemistry · 2016Article
- Ginsenoside Rb1 and compound K improve insulin signaling and inhibit ER stress-associated NLRP3 inflammasome activation in adipose tissue.Journal of ginseng research · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes mellitus is widely recognized as one of the leading causes of death and disability. While insulin insensitivity is an early phenomenon partly related to obesity, pancreatic beta-cell function declines gradually over time even before the onset of clinical hyperglycemia. Several mechanisms have been proposed to be responsible for insulin resistance, including increased non-esterified fatty acids, inflammatory cytokines, adipokines, and mitochondrial dysfunction, as well as glucotoxicity, lipotoxicity, and amyloid formation for beta-cell dysfunction. Moreover, the disease has a strong genetic component, although only a handful of genes have been identified so far. Diabetic management includes diet, exercise and combinations of antihyperglycemic drug treatment with lipid-lowering, antihypertensive, and antiplatelet therapy. Since many persons with type 2 diabetes are insulin resistant and overweight, nutrition therapy often begins with lifestyle strategies to reduce energy intake and increase energy expenditure through physical activity. These strategies should be implemented as soon as diabetes or impaired glucose homoeostasis (pre-diabetes) is diagnosed.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.