Evidence map›Paper›PMID 17564820›Full record

ArticleJournal of fluorescence2007

Specificity of cyanine dye L-21 aggregation in solutions with nucleic acids.

G Ya Guralchuk, A V Sorokin, I K Katrunov, S L Yefimova, A N Lebedenko, Yu V Malyukin, S M Yarmoluk

Abstract read
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In one paragraph

Article in Journal of fluorescence, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Cross Determination of Exciton Coherence Length in J-Aggregates.The journal of physical chemistry letters · 2022
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

G Ya GuralchukInstitute for Scintillation Materials, STC Institute for Single Crystals, NAS of Ukraine, 60 Lenin Ave., 61001 Kharkov, Ukraine.
A V Sorokin
I K Katrunov
S L Yefimova
A N Lebedenko
Yu V Malyukin
S M Yarmoluk

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optical spectroscopy experiments were used to study the features of cyanine dye 3,3'-dimethyl-9-(2-thienyl)-thiacarbocyanine iodide (L-21) aggregation in binary solutions DMF:Tris-HCl buffer (pH = 8) containing nucleic acids (DNA or RNA). The appearance of absorption and luminescence bands associated with J-aggregates and dimers that are formed within the minor groove of DNA has been observed. The model of L-21 J-aggregate structure is proposed. It has been found that dimers are the building blocks of L-21 J-aggregates. Disorientation in dimers caused by the minor groove curvature is reason of observation of Davydov splitting in absorption spectrum of L-21 J-aggregates. In the solution containing DNA the absorption and luminescence bands of L-21 J-aggregates exhibit the specific properties that allows the dye L-21 to be used as a fluorescent probe for DNA detection.

Indexed as

AnimalsCarbocyaninesColoring AgentsDNAIn Vitro TechniquesMacromolecular SubstancesModels, MolecularMolecular StructureNucleic Acid ConformationNucleic AcidsRNASolutionsSpectrometry, FluorescenceSpectrophotometryCarbocyaninesColoring AgentsDNAMacromolecular SubstancesNucleic AcidsRNASolutions

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.