ReviewBioEssays : news and reviews in molecular, cellular and developmental biology2007
Evolution of size and pattern in the social amoebas.
Review in BioEssays : news and reviews in molecular, cellular and developmental biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Article
- Amoebae: beyond pathogens- exploring their benefits and future potential.Frontiers in cellular and infection microbiology · 2024Review
- Diversity and Functional Evolution of Terpene Synthases in Dictyostelid Social Amoebae.Scientific reports · 2018Article
- Evolution of Cell-Autonomous Effector Mechanisms in Macrophages versus Non-Immune Cells.Microbiology spectrum · 2016Review
- Cancer: an emergent property of disturbed resource-rich environments? Ecology meets personalized medicine.Evolutionary applications · 2015Review
- An expanded phylogeny of social amoebas (Dictyostelia) shows increasing diversity and new morphological patterns.BMC evolutionary biology · 2011Article
- Evolutionary crossroads in developmental biology: Dictyostelium discoideum.Development (Cambridge, England) · 2011Review
- Redundant and unique roles of coronin proteins in Dictyostelium.Cellular and molecular life sciences : CMLS · 2011Article
- The Dictyostelium discoideum acaA gene is transcribed from alternative promoters during aggregation and multicellular development.PloS one · 2010Article
- A cytohesin homolog in Dictyostelium amoebae.PloS one · 2010Article
- The actinome of Dictyostelium discoideum in comparison to actins and actin-related proteins from other organisms.PloS one · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
Abstract
A fundamental goal of biology is to understand how novel phenotypes evolved through changes in existing genes. The Dictyostelia or social amoebas represent a simple form of multicellularity, where starving cells aggregate to build fruiting structures. This review summarizes efforts to provide a framework for investigating the genetic changes that generated novel morphologies in the Dictyostelia. The foundation is a recently constructed molecular phylogeny of the Dictyostelia, which was used to examine trends in the evolution of novel forms and in the divergence of genes that shape these forms. There is a major trend towards the formation of large unbranched fruiting bodies, which is correlated with the use of cyclic AMP (cAMP) as a secreted signal to coordinate cell aggregation. The role of cAMP in aggregation arose through co-option of a pathway that originally acted to coordinate fruiting body formation. The genotypic changes that caused this innovation and the role of dynamic cAMP signaling in defining fruiting body size and pattern throughout social amoeba evolution are discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.