ArticleAppetite2007
Richter and sodium appetite: from adrenalectomy to molecular biology.
Article in Appetite, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- β-Arrestin-2 Regulates Sodium Taste Processing.Hypertension (Dallas, Tex. : 1979) · 2026Article
- Rapidly decreasing phasic dopamine responses precede a hedonic switch during satiation of sodium appetite.bioRxiv : the preprint server for biology · 2026Article
- Reward Bases: A simple mechanism for adaptive acquisition of multiple reward types.PLoS computational biology · 2024Article
- FGF21 acts in the brain to drive macronutrient-specific changes in behavioral motivation and brain reward signaling.bioRxiv : the preprint server for biology · 2024Article
- Brain nuclear receptors and cardiovascular function.Cell & bioscience · 2023Review
- Sodium Intake and Disease: Another Relationship to Consider.Nutrients · 2023Review
- Oxytocin and cardiometabolic interoception: Knowing oneself affects ingestive and social behaviors.Appetite · 2022Article
- Cardiometabolic effects of DOCA-salt in male C57BL/6J mice are variably dependent on sodium and nonsodium components of diet.American journal of physiology. Regulatory, integrative and comparative physiology · 2022Article
- Protein Appetite at the Interface between Nutrient Sensing and Physiological Homeostasis.Nutrients · 2021Review
- Protein Appetite Drives Macronutrient-Related Differences in Ventral Tegmental Area Neural Activity.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- FGF21 and the Physiological Regulation of Macronutrient Preference.Endocrinology · 2020Review
- Physiological state tunes mesolimbic signaling: Lessons from sodium appetite and inspiration from Randall R. Sakai.Physiology & behavior · 2017Review
- The Perceptual Characteristics of Sodium Chloride to Sodium-Depleted Rats.Chemical senses · 2017Article
- Localisation of 11β-Hydroxysteroid Dehydrogenase Type 2 in Mineralocorticoid Receptor Expressing Magnocellular Neurosecretory Neurones of the Rat Supraoptic and Paraventricular Nuclei.Journal of neuroendocrinology · 2015Article
- Model-based and model-free Pavlovian reward learning: revaluation, revision, and revelation.Cognitive, affective & behavioral neuroscience · 2014Review
- Mineralocorticoid-induced sodium appetite and renal salt retention: evidence for common signaling and effector mechanisms.Nephron. Physiology · 2014Review
- Instant transformation of learned repulsion into motivational "wanting".Current biology : CB · 2013Article
- Blood-borne angiotensin II acts in the brain to influence behavioral and endocrine responses to psychogenic stress.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- The brain Renin-angiotensin system controls divergent efferent mechanisms to regulate fluid and energy balance.Cell metabolism · 2010Article
- The tempted brain eats: pleasure and desire circuits in obesity and eating disorders.Brain research · 2010Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Nearly three-quarters of a century ago, Curt Richter removed the adrenal glands from rats and noted that the animal's vitality was dependent on its increased consumption of sodium chloride. In doing so, Richter revealed an innate behavioral mechanism that serves to maintain the hydromineral balance of an animal faced with sodium deficit. This experiment and others like it, led to the development of a field of research devoted to the investigation of salt appetite. The following is a discussion of how Richter's initial observations gave birth to an evolving field that incorporates multiple approaches to examine the drive to consume sodium.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.