ReviewJournal of neural transmission (Vienna, Austria : 1996)2008
Botulinum toxin in the treatment of blepharospasm and hemifacial spasm.
Review in Journal of neural transmission (Vienna, Austria : 1996), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01728428 (A Multicenter, Observational Study to Evaluate Clinical Manifestation, Diagnosis and Treatment of Primary Hemifacial Spasm in Chinese Patients), which is not on this map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Multicenter, Observational Study to Evaluate Clinical Manifestation, Diagnosis and Treatment of Primary Hemifacial Spasm in Chinese Patients
Who cites it
34 citing papers in PubMed, 129 citations in OpenAlex.
- Increase lipid tear thickness after botulinum neurotoxin A injection in patients with blepharospasm and hemifacial spasm.Scientific reports · 2018Trial
- Sustained efficacy and safety of repeated incobotulinumtoxinA (Xeomin(®)) injections in blepharospasm.Journal of neural transmission (Vienna, Austria : 1996) · 2013Trial
- Hemifacial spasm and reinnervation synkinesias: long-term treatment with either Botox or Dysport.Journal of neural transmission (Vienna, Austria : 1996) · 2010Trial
- Double-blind, randomized, comparative study of Meditoxin versus Botox in the treatment of essential blepharospasm.Korean journal of ophthalmology : KJO · 2009Trial
- Methodology for preventing Botulinum toxin-A eyelid ptosis: Risk index derivation, safety rules, and evidence-graded management algorithm.World journal of methodology · 2026Review
- Article
- Ultrasound-Guided Botulinum Toxin-A Injections into the Masseter Muscle for Both Medical and Aesthetic Purposes.Toxins · 2024Review
- Objective demonstration of eyelid spasm relief with smartphone and custom software in hemifacial spasm patients.International ophthalmology · 2024Article
- Clinical Application of Botulinum Toxin for Hemifacial Spasm.Life (Basel, Switzerland) · 2023Article
- Article
- Posterior ocular structural changes and glaucoma susceptibility in patients with hemifacial spasm.Japanese journal of ophthalmology · 2021Observational
- Tardive Blepharospasm May Respond to Bilateral Pallidal Deep Brain Stimulation.Tremor and other hyperkinetic movements (New York, N.Y.) · 2021Article
- Dry Eye Disease in Hemifacial Spasm Patients Treated with Botulinum Toxin Type A.Clinical ophthalmology (Auckland, N.Z.) · 2021Article
- Impact of Upper Eyelid Surgery on Symptom Severity and Frequency in Benign Essential Blepharospasm.Journal of movement disorders · 2021Article
- Blepharospasm, Oromandibular Dystonia, and Meige Syndrome: Clinical and Genetic Update.Frontiers in neurology · 2021Review
- Efficacy of fire needle on patients of facial spasm: A protocol for systematic review and meta analysis.Medicine · 2020Article
- Evaluation of botulinum toxin effects in hemifacial spasm patients: correlation between clinical rating scales and high-speed video system measurements.Journal of neural transmission (Vienna, Austria : 1996) · 2020Article
- Serum calcium, magnesium, phosphorus, and vitamin D in benign essential blepharospasm.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2020Article
- Acupuncture therapy for patients with hemifacial spasm: A protocol of systematic review and meta-analysis.Medicine · 2019Article
- Ocular surface status in patients with hemifacial spasm under long-lasting treatment with botulinum A toxin: A comparative fellow eye study.Indian journal of ophthalmology · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Blepharospasm and hemifacial spasm are the two most common craniofacial movement disorders. Blepharospasm is a syndrome characterized by excessive or continuous eye closure related to overactivity of the orbicularis oculi and adjacent muscles bilaterally. Hemifacial spasm is a peripherally-induced movement disorder typically caused by vascular compression of cranial nerve VII (CN VII) leading to involuntary unilateral contractions of muscles used in facial expression. Treatment options for both conditions include medications, botulinum toxin, and various surgical interventions. This article summarizes the existing medical literature which indicates that botulinum toxin is the treatment of choice for blepharospasm and hemifacial spasm.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.