ArticlePlant physiology2007
Genome-wide analysis of the core DNA replication machinery in the higher plants Arabidopsis and rice.
Article in Plant physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 87 papers.
What it found
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Who cites it
87 citing papers in PubMed, 145 citations in OpenAlex.
- Exploration of the signaling pathway involving OsCSN8 in regulating the leaf angle of rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- Genome-wide identification and characterization of the RPA gene family in maize.BMC plant biology · 2026Article
- Transcriptomics Reveals an Energy-Saving Metabolic Switch in an Extremophilic Red MicroalgaInternational journal of molecular sciences · 2025Article
- The tomato gene Ty-6, encoding DNA polymerase delta subunit 1, confers broad resistance to Geminiviruses.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Identification of a novel locus qGW12/OsPUB23 regulating grain shape and weight in rice (Oryza sativa L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Article
- V2 Protein Enhances the Replication of Genomic DNA of Mulberry Crinkle Leaf Virus.International journal of molecular sciences · 2024Article
- The emerging role of SARS-CoV-2 nonstructural protein 1 (nsp1) in epigenetic regulation of host gene expression.FEMS microbiology reviews · 2024Review
- PLETHORA transcription factors promote early embryo development through induction of meristematic potential.Development (Cambridge, England) · 2024Article
- Molecular mechanisms and regulation of recombination frequency and distribution in plants.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2024Review
- A major QTL simultaneously increases the number of spikelets per spike and thousand-kernel weight in a wheat line.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Article
- Comparative protein analysis of two maize genotypes with contrasting tolerance to low temperature.BMC plant biology · 2023Article
- The Histone Chaperone Network Is Highly Conserved inInternational journal of molecular sciences · 2023Article
- A Journey to the Core of the Plant Cell Cycle.International journal of molecular sciences · 2022Review
- Cycling in a crowd: Coordination of plant cell division, growth, and cell fate.The Plant cell · 2022Review
- Antagonistic Effect of Sucrose Availability and Auxin onFrontiers in plant science · 2022Article
- A Protocol for Genome-Wide Analysis of DNA Replication Timing in Intact Root Tips.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Analysis of BRCT5 domain-containing proteins reveals a new component of DNA damage repair in Arabidopsis.Frontiers in plant science · 2022Article
- Replication protein A large subunit (RPA1a) limits chiasma formation during rice meiosis.Plant physiology · 2021Article
- The 3D Genome: From Structure to Function.International journal of molecular sciences · 2021Review
- Detection of Genes inGenes · 2021Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Core DNA replication proteins mediate the initiation, elongation, and Okazaki fragment maturation functions of DNA replication. Although this process is generally conserved in eukaryotes, important differences in the molecular architecture of the DNA replication machine and the function of individual subunits have been reported in various model systems. We have combined genome-wide bioinformatic analyses of Arabidopsis (Arabidopsis thaliana) and rice (Oryza sativa) with published experimental data to provide a comprehensive view of the core DNA replication machinery in plants. Many components identified in this analysis have not been studied previously in plant systems, including the GINS (go ichi ni san) complex (PSF1, PSF2, PSF3, and SLD5), MCM8, MCM9, MCM10, NOC3, POLA2, POLA3, POLA4, POLD3, POLD4, and RNASEH2. Our results indicate that the core DNA replication machinery from plants is more similar to vertebrates than single-celled yeasts (Saccharomyces cerevisiae), suggesting that animal models may be more relevant to plant systems. However, we also uncovered some important differences between plants and vertebrate machinery. For example, we did not identify geminin or RNASEH1 genes in plants. Our analyses also indicate that plants may be unique among eukaryotes in that they have multiple copies of numerous core DNA replication genes. This finding raises the question of whether specialized functions have evolved in some cases. This analysis establishes that the core DNA replication machinery is highly conserved across plant species and displays many features in common with other eukaryotes and some characteristics that are unique to plants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.