ReviewThe Journal of physiology2007
Glucocorticoids and insulin both modulate caloric intake through actions on the brain.
Review in The Journal of physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 96 citations in OpenAlex.
- Intranasal insulin increases regional cerebral blood flow in the insular cortex in men independently of cortisol manipulation.Human brain mapping · 2014Trial
- CRH-stimulated cortisol release and food intake in healthy, non-obese adults.Psychoneuroendocrinology · 2010Trial
- The Nutrition Facts of Comfort Foods in the United States: Results from the Census-Matched Eating in America Study.Nutrients · 2026Article
- Integrating Nutrition and Stress into Life History Stages of Wild Free-Ranging Female Pronghorn.Animals : an open access journal from MDPI · 2026Article
- Changes in hunger among pediatric patients with cancer and hematopoietic stem cell transplantation recipients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Ghrelin Receptor Signaling Is Not Required for Glucocorticoid-Induced Obesity in Male Mice.Endocrinology · 2020Article
- Article
- Sex-Specific Human Milk Composition: The Role of Infant Sex in Determining Early Life Nutrition.Nutrients · 2018Review
- Catecholaminergic projections into an interconnected forebrain network control the sensitivity of male rats to diet-induced obesity.American journal of physiology. Regulatory, integrative and comparative physiology · 2018Article
- Stress, overeating, and obesity: Insights from human studies and preclinical models.Neuroscience and biobehavioral reviews · 2017Review
- The Metabolic Implications of Glucocorticoids in a High-Fat Diet Setting and the Counter-Effects of Exercise.Metabolites · 2016Review
- Article
- Voluntary exercise improves metabolic profile in high-fat fed glucocorticoid-treated rats.Journal of applied physiology (Bethesda, Md. : 1985) · 2015Article
- Role of corticosterone in the murine enteric nervous system during fasting.American journal of physiology. Gastrointestinal and liver physiology · 2014Article
- The interplay of gender, mood, and stress hormones in the association between emotional eating and dietary behavior.The Journal of nutrition · 2014Article
- Dexamethasone-induced selenoprotein S degradation is required for adipogenesis.Journal of lipid research · 2013Article
- Stress and eating: a dual role for bombesin-like peptides.Frontiers in neuroscience · 2013Article
- Social stress interacts with diet history to promote emotional feeding in females.Psychoneuroendocrinology · 2012Article
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- Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Glucocorticoids act primarily in a feed-forward fashion on brain to activate CNS pathways that implement wanting appropriate to physiological needs. Thus, depending on the available conditions, elevated glucocorticoids may augment the behavioural want to run, fight or feed. Although glucocorticoids stimulate intake of chow, fat and sucrose, insulin appears to sculpt calorie-associated desires toward foods high in fat, acting through hepatic branch afferents of the vagus nerve. Both conditions of reduced food allowance and chronic stress excite glucocorticoid-augmented central neural networks that may lead toward ultimate abdominal obesity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.