The molecular basis of catecholaminergic polymorphic ventricular tachycardia: what are the different hypotheses regarding mechanisms?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

13 citing papers in PubMed.

1. Autosomal recessive RYR2 genetic mutation presenting as atrioventricular block and polymorphic ventricular tachycardia in a young female.HeartRhythm case reports · 2025
   Article
2. Autonomic control of ventricular function in health and disease: current state of the art.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2023
   Review
3. Cardiac Arrest From Undiagnosed Catecholaminergic Polymorphic Ventricular Tachycardia: A Case Report.Cureus · 2023
   Article
4. Inherited cardiac arrhythmias.Nature reviews. Disease primers · 2020
   Review
5. Inherited primary arrhythmia disorders: cardiac channelopathies and sports activity.Herz · 2020
   Review
6. Human pluripotent stem cell models of cardiac disease: from mechanisms to therapies.Disease models & mechanisms · 2017
   Review
7. Sudden cardiac death: focus on the genetics of channelopathies and cardiomyopathies.Journal of biomedical science · 2017
   Review
8. Treatment of catecholaminergic polymorphic ventricular tachycardia in mice using novel RyR2-modifying drugs.International journal of cardiology · 2017
   Article
9. In vitro modeling of ryanodine receptor 2 dysfunction using human induced pluripotent stem cells.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2011
   Article
10. Sudden infant death syndrome in mice with an inherited mutation in RyR2.Circulation. Arrhythmia and electrophysiology · 2009
    Article
11. Channelopathies: Brugada syndrome, long QT syndrome, short QT syndrome, and CPVT.Herz · 2009
    Review
12. DNA fragmentation in leukocytes following subacute low-dose nerve agent exposure.Cellular and molecular life sciences : CMLS · 2003
    Article
13. Animal models of arrhythmogenic cardiomyopathy.Disease models & mechanisms
    Review

Corrections and comments

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Authors and funding

1 author.

Funding

Abstract

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