ArticleDevelopment genes and evolution2007
The olig family: phylogenetic analysis and early gene expression in Xenopus tropicalis.
Article in Development genes and evolution, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Cell landscape of larval and adult Xenopus laevis at single-cell resolution.Nature communications · 2022Article
- Heparanase 2, mutated in urofacial syndrome, mediates peripheral neural development in Xenopus.Human molecular genetics · 2014Article
- Identification of Pax3 and Zic1 targets in the developing neural crest.Developmental biology · 2014Article
- Analysis of structural and molecular events associated with adult rat optic chiasm and nerves demyelination and remyelination: possible role for 3rd ventricle proliferating cells.Neuromolecular medicine · 2011Article
- Characterization of a Xenopus tropicalis endogenous retrovirus with developmental and stress-dependent expression.Journal of virology · 2011Article
- Reduced levels of survival motor neuron protein leads to aberrant motoneuron growth in a Xenopus model of muscular atrophy.Neurogenetics · 2010Article
- Spontaneous calcium spike activity in embryonic spinal neurons is regulated by developmental expression of the Na+, K+-ATPase beta3 subunit.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2009Article
- The evolution of Olig genes and their roles in myelination.Neuron glia biology · 2008Review
- Ultraconserved elements in the Olig2 promoter.PloS one · 2008Article
- Olig1 and Sox10 interact synergistically to drive myelin basic protein transcription in oligodendrocytes.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2007Article
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8 authors.
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Abstract
The olig genes form a small subfamily of basic helix-loop-helix transcription factors. They were discovered in 2000 as genes required for oligodendrocyte lineage specification. Since then, olig genes have been identified in various vertebrate species and corresponding sequences accumulated within genomic databases. Until now, three groups of olig genes have been characterized. Our phylogenetic analysis demonstrates the existence of a fourth group, which we named olig4. Genes of the four olig groups are present in actinopterygians and amphibians, whereas mammals only possess olig1, 2, and 3. We also found one olig gene in hemichordates, urochordates, and cephalochordates. Our expression study during Xenopus tropicalis embryogenesis shows that the four olig genes have very distinct expression patterns. Olig1 is very faintly expressed before the tadpole stage, whereas olig2, 3, and 4 are expressed from the gastrula stage onward. The olig3 expression during neurulation suggests a role in early anteroposterior patterning of the brain. All these results indicate that olig genes are involved in several developmental processes during early development.
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