ArticleJapanese journal of ophthalmology
Development of an instrument for measurement of light scattering at the corneal epithelial basement membrane in diabetic patients.
Article in Japanese journal of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 16 citations in OpenAlex.
- Efficacy of substance P and insulin-like growth factor-1 peptides for preventing postsurgical superficial punctate keratopathy in diabetic patients.Japanese journal of ophthalmology · 2009Trial
- Corneal Structural Alterations Under Chronic Hyperglycemia: Biomechanical and Densitometric Insights in Type 2 Diabetes with and Without Retinopathy.Beyoglu eye journal · 2026Article
- Optical Quality and Intraocular Scattering in the Diabetic Eye without Diabetic Retinopathy.Optometry and vision science : official publication of the American Academy of Optometry · 2019Article
- Corneal alteration and pathogenesis in diabetes mellitus.International journal of ophthalmology · 2019Review
- An Update on Corneal Biomechanics and Architecture in Diabetes.Journal of ophthalmology · 2019Review
- Effect of diabetic retinopathy and diabetes on the intraocular straylight in pseudophakic eyes.BMC ophthalmology · 2015Article
- Straylight, lens yellowing and aberrations of eyes in Type 1 diabetes.Biomedical optics express · 2015Article
- Optical quality of the diabetic eye: a review.Eye (London, England) · 2014Review
- Multimodal Highlighting of Structural Abnormalities in Diabetic Rat and Human Corneas.Translational vision science & technology · 2013Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeDiabetic complications are associated with abnormality of the basement membranes. We have developed a light-scattering detection system (LSDS) specifically for measurement of light scattering at the corneal epithelial basement membrane, and have determined the reproducibility and clinical significance of the results obtained by the LSDS in diabetic patients.
methodsThirty nondiabetic controls and 40 diabetic subjects participated in the study. Light scattering at the corneal epithelial basement membrane was measured with the LSDS.
resultsThe measurement of light scattering at the corneal basement membrane was found to be reproducible. The LSDS index (mean +/- SD) was 28.1 +/- 4.8 in controls, 35.7 +/- 6.3 in mild diabetic retinopathy subjects, and 42.7 +/- 8.6 in severe diabetic retinopathy subjects. This demonstrated that the LSDS index at the corneal basement membrane is proportional to the extent of diabetic retinopathy.
conclusionsMeasurement of light scattering at the corneal epithelial basement membrane is possible with the LSDS, is relatively easy to perform, and is reproducible. The LSDS may prove suitable for the early detection of diabetic ocular complications.
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