Evidence map›Paper›PMID 17553975›Full record

ArticleJournal of clinical microbiology2007

Assessment of Candida glabrata strain relatedness by pulsed-field gel electrophoresis and multilocus sequence typing.

Chi-Yang Lin, Yee-Chun Chen, Hsiu-Jung Lo, Kuo-Wei Chen, Shu-Ying Li

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Article
  2. Antifungal susceptibility, molecular epidemiology, and clinical risk factors ofFrontiers in cellular and infection microbiology · 2024
    Article
  3. Article
  4. Comparative genomic analysis of clinicalStudies in mycology · 2021
    Article
  5. Genetic diversity assessed using PFGE, MLP and MLST in Candida spp. candidemia isolates obtained from a Brazilian hospital.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Genome Comparisons ofFrontiers in microbiology · 2019
    Article
  11. Article
  12. Fungal Resistance to Echinocandins and the MDR Phenomenon inJournal of fungi (Basel, Switzerland) · 2018
    Review
  13. Article
  14. Whole Genome Sequencing of AustralianFrontiers in microbiology · 2018
    Article
  15. Candida glabrata Biofilms: How Far Have We Come?Journal of fungi (Basel, Switzerland) · 2017
    Review
  16. Article
  17. Article
  18. Genetic Drivers of Multidrug Resistance inFrontiers in microbiology · 2016
    Article
  19. Article
  20. Fluconazole Resistance Patterns in Candida Species that Colonize Women with HIV Infection.Current therapeutic research, clinical and experimental · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chi-Yang LinMycotic Diseases Laboratory, Center of Research and Diagnostics, Centers for Disease Control, Taipei, Taiwan.
Yee-Chun Chen
Hsiu-Jung Lo
Kuo-Wei Chen
Shu-Ying Li

Funding

WITHIN- AND BETWEEN-CHANNEL REPRESENTATIONSR01DC002012 · NIDCD · UNIVERSITY OF PENNSYLVANIA · PI RICHARDS, VIRGINIA M · 1994 to 2008
$2.7M
MODELING COARTICULATION: AN INTEGRATED PHONETIC APPROACHR01DC002014 · NIDCD · UNIVERSITY OF TEXAS AUSTIN · PI SUSSMAN, HARVEY M · 1994 to 2003
$1.1M
NIDCD NIH HHS R01 DC002012NIDCD NIH HHS R01 DC002014
6 · The paper itself

Abstract

In this study, 80 Candida glabrata isolates from intensive care unit and human immunodeficiency virus (HIV)-infected patients were typed by multilocus sequence typing (MLST), pulsed-field gel electrophoresis (PFGE), and mating type class determination. Among the 25 patients with multiple isolates, 19 patients (76%) contained multiple isolates exhibiting identical or highly related PFGE and MLST genotypes, which may indicate the maintenance or microvariation of one C. glabrata strain in each patient. However, isolates from six patients (24%) displayed different sequence types, PFGE genotypes, or mating type classes, which may indicate colonization with more than one clone over time or strain replacement. High correlations among PFGE genotypes, sequence types, and mating types were found (P < 0.01). MLST exhibited less discriminatory power than PFGE with BssHII. The genotypes, sequence types, and mating type classes were independent of anatomic sources, drug susceptibility, and HIV infection status.

Indexed as

Electrophoresis, Gel, Pulsed-FieldSequence Analysis, DNACandida glabrataCandidiasisCluster AnalysisGenes, Mating Type, FungalGenotypeHumansMolecular EpidemiologyMycological Typing Techniques

Identifiers

PMID17553975
PMCPMC1951215

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.