ArticleJournal of virology2007
Borna disease virus infection impairs synaptic plasticity.
Article in Journal of virology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- A Systematic Review of the Neuropathologic Findings of Post-Viral Olfactory Dysfunction: Implications and Novel Insight for the COVID-19 Pandemic.American journal of rhinology & allergy · 2021Pooled it
- Viral modulation of synaptic pruning: implications for neuropathology and brain function.Journal of virology · 2026Review
- Ex vivo study of neuroinvasive and neurotropic viruses: what is current and what is next.FEMS microbiology reviews · 2025Review
- Is There such a Thing as Post-Viral Depression?: Implications for Precision Medicine.Biomolecules & therapeutics · 2024Review
- SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice.Cell reports · 2023Article
- Transcriptome Analysis of Duck and Chicken Brains Infected with Aquatic Bird Bornavirus-1 (ABBV-1).Viruses · 2022Article
- Hippocampal expression of a virus-derived protein impairs memory in mice.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- Japanese Encephalitis Virus Infection Results in Transient Dysfunction of Memory Learning and Cholinesterase Inhibition.Molecular neurobiology · 2017Article
- Borna disease virus phosphoprotein impairs the developmental program controlling neurogenesis and reduces human GABAergic neurogenesis.PLoS pathogens · 2015Article
- A critical determinant of neurological disease associated with highly pathogenic tick-borne flavivirus in mice.Journal of virology · 2014Article
- Borna disease virus infects human neural progenitor cells and impairs neurogenesis.Journal of virology · 2012Article
- State-dependent, bidirectional modulation of neural network activity by endocannabinoids.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Neurons are MHC class I-dependent targets for CD8 T cells upon neurotropic viral infection.PLoS pathogens · 2011Article
- Intracerebral Borna disease virus infection of bank voles leading to peripheral spread and reverse transcription of viral RNA.PloS one · 2011Article
- Borna disease virus (BDV) circulating immunocomplex positivity in addicted patients in the Czech Republic: a prospective cohort analysis.BMC psychiatry · 2010Article
- Failure to detect borna disease virus antibody and RNA from peripheral blood mononuclear cells of psychiatric patients.Psychiatry investigation · 2009Article
- Mutation of the protein kinase C site in borna disease virus phosphoprotein abrogates viral interference with neuronal signaling and restores normal synaptic activity.PLoS pathogens · 2009Article
- Proteomic analysis reveals selective impediment of neuronal remodeling upon Borna disease virus infection.Journal of virology · 2008Article
- Persistent Borna Disease Virus (BDV) infection activates microglia prior to a detectable loss of granule cells in the hippocampus.Journal of neuroinflammation · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mechanisms whereby Borna disease virus (BDV) can impair neuronal function and lead to neurobehavioral disease are not well understood. To analyze the electrophysiological properties of neurons infected with BDV, we used cultures of neurons grown on multielectrode arrays, allowing a real-time monitoring of the electrical activity across the network shaped by synaptic transmission. Although infection did not affect spontaneous neuronal activity, it selectively blocked activity-dependent enhancement of neuronal network activity, one form of synaptic plasticity thought to be important for learning and memory. These findings highlight the original mechanism of the neuronal dysfunction caused by noncytolytic infection with BDV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.