ReviewWorld journal of gastroenterology2007
New animal models for hepatitis C viral infection and pathogenesis studies.
Review in World journal of gastroenterology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Modeling Liver Development and Disease in a Dish.International journal of molecular sciences · 2023Review
- Animal Models of Hepatitis C Virus Infection.Cold Spring Harbor perspectives in medicine · 2020Review
- Evaluation of Polymer Nanoformulations in Hepatoma Therapy by Established Rodent Models.Theranostics · 2019Review
- Hepatitis C Virus Infection and Vaccine Development.Journal of clinical and experimental hepatology · 2018Review
- Progress in the development of vaccines for hepatitis C virus infection.World journal of gastroenterology · 2015Review
- Visualizing hepatitis C virus infection in humanized mice.Journal of immunological methods · 2014Review
- Production and pathogenicity of hepatitis C virus core gene products.World journal of gastroenterology · 2014Review
- Development of murine models to study Hepatitis C virus induced liver pathogenesis.Indian journal of virology : an official organ of Indian Virological Society · 2013Article
- Pharmacogenetic selection of transplanted human hepatocytes in immunocompetent rats.Journal of digestive diseases · 2012Article
- Hepatocellular carcinoma xenograft supports HCV replication: a mouse model for evaluating antivirals.World journal of gastroenterology · 2011Article
- Fitness and infectivity of drug-resistant and cross-resistant hepatitis B virus mutants: why and how is it studied?Antiviral therapy · 2010Review
- Robust antiviral efficacy upon administration of a nucleoside analog to hepatitis C virus-infected chimpanzees.Antimicrobial agents and chemotherapy · 2009Article
- Mouse models in liver cancer research: a review of current literature.World journal of gastroenterology · 2008Review
- Mouse models for the study of HCV infection and virus-host interactions.Journal of hepatology · 2008Review
- Cell therapy for the diseased liver: from stem cell biology to novel models for hepatotropic human pathogens.Disease models & mechanismsArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatitis C virus (HCV) is a major cause of chronic liver disease, cirrhosis and hepatocellular carcinoma (HCC). In man, the pathobiological changes associated with HCV infection have been attributed to both the immune system and direct viral cytopathic effects. Until now, the lack of simple culture systems to infect and propagate the virus has hampered progress in understanding the viral life cycle and pathogenesis of HCV infection, including the molecular mechanisms implicated in HCV-induced HCC. This clearly demonstrates the need to develop small animal models for the study of HCV-associated pathogenesis. This review describes and discusses the development of new HCV animal models to study viral infection and investigate the direct effects of viral protein expression on liver disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.