Trial reportEuropean journal of applied physiology2007
Evidence of sex-based differences in natural killer cell responses to exercise and carbohydrate intake in children.
Trial report in European journal of applied physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed, 10 citations in OpenAlex.
- Exercise: a non-drug strategy of NK cell activation.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2024Review
- Blood immune function parameters in response to combined aerobic dance exercise and honey supplementation in adult women.Journal of traditional and complementary medicine · 2017Article
- Effects of acute exercise on markers of inflammation in pediatric chronic kidney disease: a pilot study.Pediatric nephrology (Berlin, Germany) · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Distinct natural killer (NK) cell subsets (CD56bright and CD56dim) are mobilized with exercise and these cells may serve adaptive functions. We determined the distribution of NK cell subsets in response to exercise and carbohydrate (CHO) intake in young girls and compared these responses with previous findings in young boys of the same age. Twelve girls (12 years old) cycled for 60 min at 70% VO2max while drinking 6% CHO or flavoured water. Blood was collected at rest, during (30 and 60 min) and following (30 and 60 min) exercise to identify NK cells as CD3-CD56bright or CD3-CD56dim. CD69 expression on total CD3-CD56+ cells was also determined. A trend (P=0.07) was found for a trial x time interaction in CD56dim cell counts, with values lower with CHO than with water. CHO intake did not influence CD56bright responses (P>or=0.39). The CD56bright:CD56dim ratio increased during recovery from exercise (P<0.001), compared to rest, with no effect of CHO intake (P=0.48). CD69 expression was not different between exercise or recovery and rest. Like young boys, girls experience an elevated CD56bright:CD56dim ratio during recovery from exercise and CHO intake attenuates the exercise-induced CD56dim but not CD56bright cell response. Unlike young boys, girls do not experience a CHO-induced increase in the CD56bright:CD56dim ratio during recovery and CD69 expression does not increase on CD3-CD56+ cells during recovery. We conclude that even in young children sex-based differences exist in the NK cell response to exercise and CHO intake.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.