ArticleEuropean radiology2007
Perfusion CT in acute stroke: prediction of vessel recanalization and clinical outcome in intravenous thrombolytic therapy.
Article in European radiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- CBV_ASPECTS Improvement over CT_ASPECTS on Determining Irreversible Ischemic Lesion Decreases over Time.Interventional neurology · 2016Article
- Thrombus length discrepancy on dual-phase CT can predict clinical outcome in acute ischemic stroke.European radiology · 2016Article
- Predictors of reperfusion in patients with acute ischemic stroke.AJNR. American journal of neuroradiology · 2015Article
- Toward patient-tailored perfusion thresholds for prediction of stroke outcome.AJNR. American journal of neuroradiology · 2014Article
- Time-resolved assessment of collateral flow using 4D CT angiography in large-vessel occlusion stroke.European radiology · 2014Article
- Article
- Acute stroke: a comparison of different CT perfusion algorithms and validation of ischaemic lesions by follow-up imaging.European radiology · 2012Article
- Article
- Feasibility of cerebral blood volume mapping by flat panel detector CT in the angiography suite: first experience in patients with acute middle cerebral artery occlusions.AJNR. American journal of neuroradiology · 2012Article
- Evaluation of CT perfusion in the setting of cerebral ischemia: patterns and pitfalls.AJNR. American journal of neuroradiology · 2010Review
- Intra-arterial stroke therapy: an assessment of demand and available work force.AJNR. American journal of neuroradiology · 2009Review
- Correlation of volumetric mismatch and mismatch of Alberta Stroke Program Early CT Scores on CT perfusion maps.Neuroradiology · 2009Article
- Renal safety of CT angiography and perfusion imaging in the emergency evaluation of acute stroke.AJNR. American journal of neuroradiology · 2008Article
- Prediction of clinical outcome with baseline and 24-hour perfusion CT in acute middle cerebral artery territory ischemic stroke treated with intravenous recanalization therapy.Neuroradiology · 2008Article
- Accuracy of the Alberta Stroke Program Early CT Score during the first 3 hours of middle cerebral artery stroke: comparison of noncontrast CT, CT angiography source images, and CT perfusion.AJNR. American journal of neuroradiology · 2008Article
- Endovascular treatment of acute stroke.Current treatment options in neurology · 2007Article
- CT Perfusion ASPECTS in the Evaluation of Acute Ischemic Stroke: Thrombolytic Therapy Perspective.Cerebrovascular diseases extraArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study evaluated perfusion computed tomography (PCT) for the prediction of vessel recanalization and clinical outcome in patients undergoing intravenous thrombolysis. Thirty-nine patients with acute ischemic stroke of the middle cerebral artery territory underwent intravenous thrombolysis within 3 h of symptom onset. They all had non-enhanced CT (NECT), PCT, and CT angiography (CTA) before treatment. The Alberta Stroke Program Early Computed Tomography (ASPECT) score was applied to NECT and PCT maps to assess the extent of ischemia. CTA was assessed for the site of vessel occlusion. The National Institute of Health Stroke Scale (NIHSS) score was used for initial clinical assessment. Three-month clinical outcome was assessed using the modified Rankin scale. Vessel recanalization was determined by follow-up ultrasound. Of the PCT maps, a cerebral blood volume (CBV) ASPECT score of >6 versus < or =6 was the best predictor for clinical outcome (odds ratio, 31.43; 95% confidence interval, 3.41-289.58; P < 0.002), and was superior to NIHSS, NECT and CTA. No significant differences in ASPECT scores were found for the prediction of vessel recanalization. ASPECT score applied to PCT maps in acute stroke patients predicts the clinical outcome of intravenous thrombolysis and is superior to both early NECT and clinical parameters.
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