ArticleEvidence-based complementary and alternative medicine : eCAM2007
Immunology and homeopathy. 5. The rationale of the 'Simile'.
Article in Evidence-based complementary and alternative medicine : eCAM, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Homeopathic Oscillococcinum® for preventing and treating influenza and influenza-like illness.The Cochrane database of systematic reviews · 2015Pooled it
- Low-dose Drosera rotundifolia induces gene expression changes in 16HBE human bronchial epithelial cells.Scientific reports · 2021Article
- Advances in Integrative Nanomedicine for Improving Infectious Disease Treatment in Public Health.European journal of integrative medicine · 2013Article
- Testing the nanoparticle-allostatic cross-adaptation-sensitization model for homeopathic remedy effects.Homeopathy : the journal of the Faculty of Homeopathy · 2013Article
- Immunomodulation of Homeopathic Thymulin 5CH in a BCG-Induced Granuloma Model.Evidence-based complementary and alternative medicine : eCAM · 2013Article
- A model for homeopathic remedy effects: low dose nanoparticles, allostatic cross-adaptation, and time-dependent sensitization in a complex adaptive system.BMC complementary and alternative medicine · 2012Article
- Highly diluted medication reduces parasitemia and improves experimental infection evolution by Trypanosoma cruzi.BMC research notes · 2012Article
- Inhibition of peripheral blood neutrophil oxidative burst in periodontitis patients with a homeopathic medication Traumeel S.Medical science monitor : international medical journal of experimental and clinical research · 2011Article
- Treatment with at homeopathic complex medication modulates mononuclear bone marrow cell differentiation.Evidence-based complementary and alternative medicine : eCAM · 2011Article
- Homeopathic Doses of Gelsemium sempervirens Improve the Behavior of Mice in Response to Novel Environments.Evidence-based complementary and alternative medicine : eCAM · 2011Article
- Evaluating complementary therapies for canine osteoarthritis--Part II: a homeopathic combination preparation (Zeel).Evidence-based complementary and alternative medicine : eCAM · 2009Article
- Homeopathy and integrative medicine: keeping an open mind.Journal of medicine and the personArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The foundation of homeopathic medicine is the 'Similia Principle', also known as the 'Principle of Similarity' or also as the 'Simile', which reflects the inversion of pharmacological effects in healthy subjects as compared with sick ones. This article describes the inversion of effects, a widespread medical phenomenon, through three possible mechanisms: non-linearity of dose-response relationship, different initial pathophysiological states of the organism, and pharmacodynamics of body response to the medicine. Based on the systemic networks which play an important role in response to stress, a unitary and general model is designed: homeopathic medicines could interact with sensitive (primed) regulation systems through complex information, which simulate the disorders of natural disease. Reorganization of regulation systems, through a coherent response to the medicine, could pave the way to the healing of the cellular, tissue and neuro-immuno-endocrine homeodynamics. Preliminary evidence is suggesting that even ultra-low doses and high-dilutions of drugs may incorporate structural or frequency information and interact with chaotic dynamics and physical-electromagnetic levels of regulation. From the clinical standpoint, the 'simile' can be regarded as a heuristic principle, according to which the detailed knowledge of pathogenic effects of drugs, associated with careful analysis of signs and symptoms of the ill subject, could assist in identifying homeopathic remedies with high grade of specificity for the individual case.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.