ArticleEvidence-based complementary and alternative medicine : eCAM2007
Traditional phytochemistry: identification of drug by 'taste'.
Article in Evidence-based complementary and alternative medicine : eCAM, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- A transdisciplinary framework for managing metabolic dysfunction associated steatotic liver disease.Frontiers in pharmacology · 2026Article
- Article
- Phytochemicals and Inflammation: Is Bitter Better?Plants (Basel, Switzerland) · 2022Article
- Exploring Ayurvedic Knowledge on Food and Health for Providing Innovative Solutions to Contemporary Healthcare.Frontiers in public health · 2016Review
- Ethnomedicinal plants used by traditional healers in Phatthalung Province, Peninsular Thailand.Journal of ethnobiology and ethnomedicine · 2015Article
- Rasa Nirdhāraṇa (assessment of taste) of Leonotis nepetifolia (L.) R. Br.: A preliminary study in healthy volunteers.Ancient science of life · 2014Article
- Cyperus rotundus, a substitute for Aconitum heterophyllum: Studies on the Ayurvedic concept of Abhava Pratinidhi Dravya (drug substitution).Journal of Ayurveda and integrative medicine · 2010Article
- Building bridges between Ayurveda and Modern Science.International journal of Ayurveda research · 2010Article
- Antioxidant activity of 45 Chinese herbs and the relationship with their TCM characteristics.Evidence-based complementary and alternative medicine : eCAM · 2008Article
- Evolution of dietary preferences and the innate urge to heal: Drug discovery lessons from Ayurveda.Journal of Ayurveda and integrative medicineReview
- Spectroscopic and E-tongue evaluation of medicinal plants: A taste of how rasa can be studied.Journal of Ayurveda and integrative medicineArticle
- The scientific basis of rasa (taste) of a substance as a tool to explore its pharmacological behavior.Ancient science of lifeReview
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Authors and funding
3 authors.
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Abstract
Ayurveda, the system of traditional medicine from India, holds that 'Rasa', a concept roughly corresponding to taste, is a basis for identifying pharmacological properties of plants and other materia medica used in Dravyaguna-its system of phytomedicine. This idea has recently found support in studies of ibuprofen, the pharmacological properties of which are similar to those of oleocanthal, because the two substances have very similar tastes. This paper discusses a possible scientific approach to understanding the Ayurvedic (hypo)thesis in terms of the stereochemical basis of both pharamaco-activity and taste, and the numbers of possible pharmaco-active compounds that 'Rasa' may be able to distinguish. We conclude that molecules binding to a specific enzyme active site should have their own 'Rasa', and that the number of different subjectively experienced 'tastes' is more than enough to distinguish between molecular shapes binding to all enzyme active sites in the body.
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Registered trials
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