ArticleNeurology2007
Prevalence of asymptomatic intracranial atherosclerosis in high-risk patients.
Article in Neurology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06902740 (PCSK9 Inhibitor With Statin Therapy for Asymptomatic Intracranial Atherosclerosis), which is not on this map. Cited by 53 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
PCSK9 Inhibitor With Statin Therapy for Asymptomatic Intracranial Atherosclerosis (PISTIAS-2): A Multicenter, Open-label, Blinded-endpoint, Randomized Controlled Trial
Who cites it
53 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis.The Cochrane database of systematic reviews · 2023Pooled it
- Endovascular therapy versus medical treatment for symptomatic intracranial artery stenosis.The Cochrane database of systematic reviews · 2020Pooled it
- Association of Newly Found Asymptomatic Intracranial Artery Stenosis and Ideal Cardiovascular Health Metrics in Chinese Community Population.Scientific reports · 2020Trial
- Asymptomatic polyvascular abnormalities in community (APAC) study in China: objectives, design and baseline characteristics.PloS one · 2013Trial
- Unmasking the Imitators: Challenges in Identifying Intracranial Atherosclerosis-Related Large Vessel Occlusion Mimics During Mechanical Thrombectomy.Stroke (Hoboken, N.J.) · 2025Review
- Intracranial atherosclerotic disease and neurodegeneration: a narrative review and plausible mechanisms.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2024Review
- Review
- A bibliometric analysis of the 100 most-cited clinical articles in the research of intracranial artery stenosis and intracranial atherosclerosis.Surgical neurology international · 2024Review
- Association of visceral adiposity index with asymptomatic intracranial arterial stenosis: a population-based study in Shandong, China.Lipids in health and disease · 2023Article
- Prevalence and Risk Factors Comparison of Anterior and Posterior Intracranial Arterial Stenosis.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Research progress on risk factors related to intracranial artery, carotid artery, and coronary artery stenosis.Frontiers in cardiovascular medicine · 2022Review
- Long-term prognosis of patients with stroke associated with middle cerebral artery occlusion. Single-centre registration study.Archives of medical science : AMS · 2022Article
- Determinants and Outcomes of Asymptomatic Intracranial Atherosclerotic Stenosis.Journal of the American College of Cardiology · 2021 · on this mapArticle
- Vessel wall MR imaging of intracranial atherosclerosis.Cardiovascular diagnosis and therapy · 2020Review
- Kongcun Town Asymptomatic Intracranial Artery Stenosis study in Shandong, China: cohort profile.BMJ open · 2020Article
- Association Between Cumulative Exposure to Increased Low-Density Lipoprotein Cholesterol and the Prevalence of Asymptomatic Intracranial Atherosclerotic Stenosis.Frontiers in neurology · 2020Article
- Correlation between Metabolic Syndrome and Intracranial versus Extracranial Arteriosclerosis among Chinese Patients with Stroke.Iranian journal of public health · 2019Article
- Intensive Lipid-Lowering Therapy Ameliorates Asymptomatic Intracranial Atherosclerosis.Aging and disease · 2019 · on this mapArticle
- Intracranial atherosclerotic disease.Neurobiology of disease · 2019Review
- Novel Insights on Systemic and Brain Aging, Stroke, Amyotrophic Lateral Sclerosis, and Alzheimer's Disease.Aging and disease · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We used transcranial Doppler to screen 3,057 patients who had at least one vascular risk factor of hypertension, diabetes, or hyperlipidemia and found 385 (12.6%) had middle cerebral artery stenosis. Elderly, hypertension, diabetes, and hyperlipidemia were associated factors. The prevalence escalated quadratically with increasing number of associated factors: from 7.2% for one, to 29.6% for four associated factors. Asymptomatic middle cerebral artery stenosis is common in patients with vascular risk factors.
Indexed as
Identifiers
17548555What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.