Evidence map›Paper›PMID 17547760›Full record

Trial reportBMC health services research2007

Implementing a guideline for the treatment of type 2 diabetics: results of a cluster-randomized controlled trial (C-RCT).

Carla Perria, Donatella Mandolini, Carmelina Guerrera, Tom Jefferson, Paolo Billi, Virgilio Calzini, Alfonso Fiorillo, Giuseppe Grasso, Sergio Leotta, Walter Marrocco and 2 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC health services research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 6 pooled it
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 6 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  4. Interventions to increase attendance for diabetic retinopathy screening.The Cochrane database of systematic reviews · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Carla PerriaCommunity Health Unit, Lazio Region Public Health Agency, Rome, Italy. perria@asplazio.it
Donatella Mandolini
Carmelina Guerrera
Tom Jefferson
Paolo Billi
Virgilio Calzini
Alfonso Fiorillo
Giuseppe Grasso
Sergio Leotta
Walter Marrocco
Concetta Suraci
Amina Pasquarella
Agenzia Regionale Parchi · ITOspedale Sandro Pertini · ITRegione Lazio

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Italy many diabetics still lack adequate care in general practice. We assessed the effectiveness of different strategies for the implementation of an evidence-based guideline for the management of non-complicated type 2 diabetes among General Practitioners (GPs) of Lazio region.

methodsThree-arm cluster-randomised controlled trial with GPs as units of randomisation (clusters). 252 GPs were randomised either to an active strategy (training module with administration of the guideline), or to a passive dissemination (administration of the guideline only), or to usual care (control). Data on prescriptions of tests and drugs were collected by existing information systems, whereas patients' data came from GPs' databases. Process outcomes were measured at the cluster level one year after the intervention. Primary outcomes concerned the measurement of glycosilated haemoglobin and the commissioning of micro- and macrovascular complications assessment tests. In order to assess the physicians' drug prescribing behaviour secondary outcomes were also calculated.

resultsGPs identified 6395 uncomplicated type 2 patients with a high prevalence of cardiovascular risk factors. Data on GPs baseline performance show low proportions of glycosilated haemoglobin assessments. Results of the C-RCT analysis indicate that the active implementation strategy was ineffective relating to all primary outcomes (respectively, OR 1.06 [95% IC: 0.76-1.46]; OR 1.07 [95% IC: 0.80-1.43]; OR 1.4 [95% IC:0.91-2.16]. Similarly, passive dissemination of the guideline showed no effect.

conclusionIn our region compliance of GPs with guidelines was not enhanced by a structured learning programme. Implementation through organizational measures appears to be essential to induce behavioural changes.

trial registrationISRCTN80116232.

Indexed as

Guideline AdherenceCluster AnalysisDiabetes Mellitus, Type 2Dose-Response Relationship, DrugDrug Administration ScheduleDrug UtilizationEvidence-Based MedicineFamily PracticeFemaleHumansHypoglycemic AgentsItalyMalePractice Patterns, Physicians'Hypoglycemic Agents

Identifiers

PMID17547760
PMCPMC1904445
OpenAlexW2071779676

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.