ArticleDevelopmental biology2007
Can tissue surface tension drive somite formation?
Article in Developmental biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- A chemo-mechanical model of endoderm movements driving elongation of the amniote hindgut.Development (Cambridge, England) · 2023Article
- Article
- Article
- Type IV Pilin Post-Translational Modifications Modulate Material Properties of Bacterial Colonies.Biophysical journal · 2019Article
- 4D imaging reveals stage dependent random and directed cell motion during somite morphogenesis.Scientific reports · 2018Article
- Water in the human body: An anesthesiologist's perspective on the connection between physicochemical properties of water and physiologic relevance.Annals of medicine and surgery (2012) · 2018Review
- Timing by rhythms: Daily clocks and developmental rulers.Development, growth & differentiation · 2016Review
- Mechanics of tissue compaction.Seminars in cell & developmental biology · 2015Review
- Segment-specific adhesion as a driver of convergent extension.PLoS computational biology · 2015Article
- Surface tension in human pathophysiology and its application as a medical diagnostic tool.BioImpacts : BI · 2015Review
- Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation.Developmental cell · 2011Article
- Physics and the canalization of morphogenesis: a grand challenge in organismal biology.Physical biology · 2011Article
- Mathematical models for somite formation.Current topics in developmental biology · 2008Review
- Coordinated action of N-CAM, N-cadherin, EphA4, and ephrinB2 translates genetic prepatterns into structure during somitogenesis in chick.Current topics in developmental biology · 2008Review
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The prevailing model of somitogenesis supposes that the presomitic mesoderm is segmented into somites by a clock and wavefront mechanism. During segmentation, mesenchymal cells undergo compaction, followed by a detachment of the presumptive somite from the rest of the presomitic mesoderm and the subsequent morphological changes leading to rounded somites. We investigate the possibility that minimization of tissue surface tension drives the somite sculpting processes. Given the time in which somite formation occurs and the high bulk viscosities of tissues, we find that only small changes in shape and form of tissue typically occur through cell movement driven by tissue surface tension. This is particularly true for somitogenesis in the zebrafish. Hence it is unlikely that such processes are the sole and major driving force behind somite formation. We propose a simple chemotactic mechanism that together with heightened adhesion can account for the morphological changes in the time allotted for somite formation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.