Trial reportBMC pediatrics2007
Computerized acoustic assessment of treatment efficacy of nebulized epinephrine and albuterol in RSV bronchiolitis.
Trial report in BMC pediatrics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Systematic review of instruments aimed at evaluating the severity of bronchiolitis.Paediatric respiratory reviews · 2018Pooled it
- Bronchodilators for bronchiolitis.The Cochrane database of systematic reviews · 2014Pooled it
- Epinephrine for bronchiolitis.The Cochrane database of systematic reviews · 2011Pooled it
- Nebulized Magnesium Sulfate in Acute Bronchiolitis: A Randomized Controlled Trial.Indian journal of pediatrics · 2015Trial
- Wheeze Recognition Algorithm for Remote Medical Care Device in Children: Validation Study.JMIR pediatrics and parenting · 2021Article
- Article
- Network Meta-Analysis Comparing the Efficacy of Therapeutic Treatments for Bronchiolitis in Children.JPEN. Journal of parenteral and enteral nutrition · 2018Article
- Validation of computerized wheeze detection in young infants during the first months of life.BMC pediatrics · 2014Article
- Comparison of epinephrine to salbutamol in acute bronchiolitis.Iranian journal of pediatrics · 2012Article
- An unidentified monster in the bed--assessing nocturnal asthma in children.McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimWe evaluated the use of computerized quantification of wheezing and crackles compared to a clinical score in assessing the effect of inhaled albuterol or inhaled epinephrine in infants with RSV bronchiolitis.
methodsComputerized lung sounds analysis with quantification of wheezing and crackles and a clinical score were used during a double blind, randomized, controlled nebulized treatment pilot study. Infants were randomized to receive a single dose of 1 mgr nebulized l-epinephrine or 2.5 mgr nebulized albuterol. Computerized quantification of wheezing and crackles (PulmoTrack) and a clinical score were performed prior to, 10 minutes post and 30 minutes post treatment. Results were analyzed with Student's t-test for independent samples, Mann-Whitney U test and Wilcoxon test.
results15 children received albuterol, 12 received epinephrine. The groups were identical at baseline. Satisfactory lung sounds recording and analysis was achieved in all subjects. There was no significant change in objective quantification of wheezes and crackles or in the total clinical scores either within the groups or between the groups. There was also no difference in oxygen saturation and respiratory distress.
conclusionComputerized lung sound analysis is feasible in young infants with RSV bronchiolitis and provides a non-invasive, quantitative measure of wheezing and crackles in these infants.
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