ArticleEuropean journal of pediatrics2008
Prolonged follow up of seven patients affected by hepatosplenic granulomata due to cat-scratch disease.
Article in European journal of pediatrics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 16 citations in OpenAlex.
- A Retrospective Analysis of SystemicMicroorganisms · 2024Article
- Update on Fever of Unknown Origin in Children: Focus on Etiologies and Clinical Approach.Children (Basel, Switzerland) · 2023Review
- Hepatosplenic cat scratch disease in immunocompetent adults: report of 3 cases and review of the literature.Medicine · 2014Review
- Atypical presentation of cat-scratch disease in an immunocompetent child with serological and pathological evidence.Case reports in pediatrics · 2014Article
- Outcomes of splenectomy in patients with common variable immunodeficiency (CVID): a survey of 45 patients.Clinical and experimental immunology · 2013Article
- Systemic Bartonella henselae Infection in Immunocompetent Adult Presenting as Fever of Unknown Origin.Case reports in medicine · 2011Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study is a retrospective analysis of seven patients with hypoechogenic lesions in the liver and/or spleen due to Bartonella henselae, who were followed from 1998 through to 2005 by the Department of Pediatrics, Turin University. In addition to showing constitutional symptoms, four children had skin lesions suggestive of injuries inflicted by cats, and one child had a history of exposure to cats. The origin of the infection remained undefined in the other two patients. Humoral tests enabled a precise diagnosis in all children. Treatment with macrolides or combinations of two active antibiotics for at least 2-3 weeks led to the definitive clearance of infection, although residual intraparenchymal lesions persisted in five patients for several months or years. Conclusion B. henselae serology allows an easy diagnosis of multiple hepatosplenic granulomata, a clinical picture that appears to be under-recognized. Macrolides or a combination of two active antibiotics for 2-3 weeks leads to a rapid clinical response and a definitive clearance of infection.
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