ArticleNutritional neuroscience
High dietary cholesterol facilitates classical conditioning of the rabbit's nictitating membrane response.
Article in Nutritional neuroscience. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 20 citations in OpenAlex.
- Sex differences in a rabbit eyeblink conditioning model of PTSD.Neurobiology of learning and memory · 2018Article
- Dietary cholesterol concentration affects synaptic plasticity and dendrite spine morphology of rabbit hippocampal neurons.Brain research · 2015Article
- The impact of hippocampal lesions on trace-eyeblink conditioning and forebrain-cerebellar interactions.Behavioral neuroscience · 2015Review
- Eyeblink classical conditioning and post-traumatic stress disorder - a model systems approach.Frontiers in psychiatry · 2015Review
- Cholesterol diet counteracts repeated anesthesia/infusion-induced cognitive deficits in male Brown Norway rats.Neurobiology of learning and memory · 2013Article
- Dietary cholesterol degrades rabbit long term memory for discrimination learning but facilitates acquisition of discrimination reversal.Neurobiology of learning and memory · 2013Article
- Cholesterol and copper affect learning and memory in the rabbit.International journal of Alzheimer's disease · 2013Review
- Predictors of susceptibility and resilience in an animal model of posttraumatic stress disorder.Behavioral neuroscience · 2012Article
- Cholesterol increases ventricular volume in a rabbit model of Alzheimer's disease.Journal of Alzheimer's disease : JAD · 2012Article
- Dietary Cholesterol Concentration and Duration Degrade Long-Term Memory of Classical Conditioning of the Rabbit's Nictitating Membrane Response.International journal of Alzheimer's disease · 2012Article
- Classical conditioning and conditioning-specific reflex modification of rabbit heart rate as a function of unconditioned stimulus location.Behavioral neuroscience · 2011Article
- Dietary cholesterol modulates the excitability of rabbit hippocampal CA1 pyramidal neurons.Neuroscience letters · 2010Article
- The effects of cholesterol on learning and memory.Neuroscience and biobehavioral reviews · 2010Review
- Dietary cholesterol impairs memory and memory increases brain cholesterol and sulfatide levels.Behavioral neuroscience · 2010Article
- Classical conditioning of the rabbit's nictitating membrane response is a function of the duration of dietary cholesterol.Nutritional neuroscienceArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
Studies have shown that modifying dietary cholesterol may improve learning and that serum cholesterol levels can be positively correlated with cognitive performance. Rabbits fed a 0, 0.5, 1 or 2% cholesterol diet for eight weeks and 0.12 ppm copper added to their drinking water received trace and then delay classical conditioning pairing tone with corneal air puff during which movement of the nictitating membrane (NM) across the eye was monitored. We found that the level of classical conditioning and conditioning-specific reflex modification (CRM) as well as the number of beta amyloid-labeled neurons in the cortex and hippocampus were a function of the concentration of cholesterol in the diet. The data provide support for the idea that dietary cholesterol may facilitate learning and memory.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.