ArticleJournal of clinical microbiology2007
Host genetic resistance to symptomatic norovirus (GGII.4) infections in Denmark.
Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.
- A genome-wide association meta-analysis of diarrhoeal disease in young children identifies FUT2 locus and provides plausible biological pathways.Human molecular genetics · 2016Pooled it
- Identification of Milk and Cheese Intake Biomarkers in Healthy Adults Reveals High Interindividual Variability of Lewis System-Related Oligosaccharides.The Journal of nutrition · 2020Trial
- Genetic Associations with Coronavirus Susceptibility and Disease Severity.Advances in experimental medicine and biology · 2023Review
- Risk Assessment of Norovirus Illness from Consumption of Raw Oysters in the United States and in Canada.Risk analysis : an official publication of the Society for Risk Analysis · 2022Article
- Targeted Profiling of Immunological Genes during Norovirus Replication in Human Intestinal Enteroids.Viruses · 2021Article
- Norovirus Seroprevalence among Adults in the United States: Analysis of NHANES Serum Specimens from 1999-2000 and 2003-2004.Viruses · 2020Article
- Review
- FUT2 Genetic Variants and Reported Respiratory and Gastrointestinal Illnesses During Infancy.The Journal of infectious diseases · 2019Article
- Infection's Sweet Tooth: How Glycans Mediate Infection and Disease Susceptibility.Trends in microbiology · 2018Review
- Development of a Surrogate Neutralization Assay for Norovirus Vaccine Evaluation at the Cellular Level.Viruses · 2018Article
- Article
- Human Sera Collected between 1979 and 2010 Possess Blocking-Antibody Titers to Pandemic GII.4 Noroviruses Isolated over Three Decades.Journal of virology · 2017Article
- Recent advances in understanding noroviruses.F1000Research · 2017Review
- Norovirus prevalence and estimated viral load in symptomatic and asymptomatic children from rural communities of Vhembe district, South Africa.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2016Article
- Tulane virus recognizes sialic acids as cellular receptors.Scientific reports · 2015Article
- Norovirus Infection and Disease in an Ecuadorian Birth Cohort: Association of Certain Norovirus Genotypes With Host FUT2 Secretor Status.The Journal of infectious diseases · 2015Article
- Fucosyltransferase 2: a genetic risk factor for primary sclerosing cholangitis and Crohn's disease--a comprehensive review.Clinical reviews in allergy & immunology · 2015Review
- Article
- Article
- Two gastroenteritis outbreaks caused by GII Noroviruses: host susceptibility and HBGA phenotypes.PloS one · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A total of 61 individuals involved in five norovirus outbreaks in Denmark were genotyped at nucleotides 428 and 571 of the FUT2 gene, determining secretor status, i.e., the presence of ABH antigens in secretions and on mucosa. A strong correlation (P = 0.003) was found between the secretor phenotype and symptomatic disease, extending previous knowledge and confirming that nonsense mutations in the FUT2 gene provide protection against symptomatic norovirus (GGII.4) infections.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.