ArticleNucleic acids research2007
MobilomeFINDER: web-based tools for in silico and experimental discovery of bacterial genomic islands.
Article in Nucleic acids research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- MOBHunter: a data integration platform for identification and classification of mobile genetic elements in microbial genomes.Nucleic acids research · 2025Article
- The Pseudomonas aeruginosa Resistome: Permanent and Transient Antibiotic Resistance, an Overview.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Article
- Metagenomic-based surveillance systems for antibiotic resistance in non-clinical settings.Frontiers in microbiology · 2022Review
- Reconstructing the Phylogeny of Corynebacteriales while Accounting for Horizontal Gene Transfer.Genome biology and evolution · 2020Article
- Microbial genomic island discovery, visualization and analysis.Briefings in bioinformatics · 2019Review
- Involvement of β-Carbonic Anhydrase Genes in Bacterial Genomic Islands and Their Horizontal Transfer to Protists.Applied and environmental microbiology · 2018Article
- xenoGI: reconstructing the history of genomic island insertions in clades of closely related bacteria.BMC bioinformatics · 2018Article
- Colonization, Infection, and the Accessory Genome ofFrontiers in cellular and infection microbiology · 2018Review
- Article
- Zisland Explorer: detect genomic islands by combining homogeneity and heterogeneity properties.Briefings in bioinformatics · 2017Article
- Identification and analysis of genomic islands in Burkholderia cenocepacia AU 1054 with emphasis on pathogenicity islands.BMC microbiology · 2017Article
- A Novel Approach to Helicobacter pylori Pan-Genome Analysis for Identification of Genomic Islands.PloS one · 2016Article
- Klebsiella pneumoniae Asparagine tDNAs Are Integration Hotspots for Different Genomic Islands Encoding Microcin E492 Production Determinants and Other Putative Virulence Factors Present in Hypervirulent Strains.Frontiers in microbiology · 2016Article
- Computational methods for predicting genomic islands in microbial genomes.Computational and structural biotechnology journal · 2016Review
- Article
- Complete genome sequence of hypervirulent and outbreak-associated Acinetobacter baumannii strain LAC-4: epidemiology, resistance genetic determinants and potential virulence factors.Scientific reports · 2015Article
- Article
- Characterization of the core and accessory genomes of Pseudomonas aeruginosa using bioinformatic tools Spine and AGEnt.BMC genomics · 2014Article
- Identification of Horizontally-transferred Genomic Islands and Genome Segmentation Points by Using the GC Profile Method.Current genomics · 2014Article
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Authors and funding
11 authors.
Funding
Abstract
MobilomeFINDER (http://mml.sjtu.edu.cn/MobilomeFINDER) is an interactive online tool that facilitates bacterial genomic island or 'mobile genome' (mobilome) discovery; it integrates the ArrayOme and tRNAcc software packages. ArrayOme utilizes a microarray-derived comparative genomic hybridization input data set to generate 'inferred contigs' produced by merging adjacent genes classified as 'present'. Collectively these 'fragments' represent a hypothetical 'microarray-visualized genome (MVG)'. ArrayOme permits recognition of discordances between physical genome and MVG sizes, thereby enabling identification of strains rich in microarray-elusive novel genes. Individual tRNAcc tools facilitate automated identification of genomic islands by comparative analysis of the contents and contexts of tRNA sites and other integration hotspots in closely related sequenced genomes. Accessory tools facilitate design of hotspot-flanking primers for in silico and/or wet-science-based interrogation of cognate loci in unsequenced strains and analysis of islands for features suggestive of foreign origins; island-specific and genome-contextual features are tabulated and represented in schematic and graphical forms. To date we have used MobilomeFINDER to analyse several Enterobacteriaceae, Pseudomonas aeruginosa and Streptococcus suis genomes. MobilomeFINDER enables high-throughput island identification and characterization through increased exploitation of emerging sequence data and PCR-based profiling of unsequenced test strains; subsequent targeted yeast recombination-based capture permits full-length sequencing and detailed functional studies of novel genomic islands.
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