Evidence map›Paper›PMID 17536177›Full record

ReviewJournal of biosciences2007

Mechanisms of HSP72 release.

Alexzander Asea

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of biosciences, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Trial
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  12. Review
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  14. Muscle heat shock protein 70 predicts insulin resistance with aging.The journals of gerontology. Series A, Biological sciences and medical sciences · 2015
    Article
  15. Article
  16. Article
  17. A protective Hsp70-TLR4 pathway in lethal oxidant lung injury.Journal of immunology (Baltimore, Md. : 1950) · 2013
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Alexzander AseaDivision of Investigative Pathology, Scott and White Clinic, Texas A&M University System Health Science Center College of Medicine, 2401 South 31st Street, Temple, TX 76508, USA. asea@medicine.tamhsc.edu

Funding

Circulating HSP70 in Hyperthermia and Cancer TherapyR01CA091889 · NCI · SCOTT AND WHITE MEMORIAL HOSPITAL · PI ASEA, ALEXZANDER A · 2003 to 2006
$1.3M
NCI NIH HHS R01CA91889
6 · The paper itself

Abstract

Currently two mechanisms are recognized by which heat shock proteins (HSP) are released from cells; a passive release mechanism, including necrotic cell death, severe blunt trauma, surgery and following infection with lytic viruses, and an active release mechanism which involves the non classical protein release pathway. HSPs are released both as free HSP and within exosomes. This review covers recent findings on the mechanism by which stress induces the release of HSP72 into the circulation and the biological significance of circulating HSP72 to host defense against disease.

Indexed as

AnimalsHSP72 Heat-Shock ProteinsHumansNeoplasmsStress, PhysiologicalHSP72 Heat-Shock Proteins

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.