ReviewJournal of biosciences2007
Thermosensors in eubacteria: role and evolution.
Review in Journal of biosciences, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 39 citations in OpenAlex.
- Proteomic and phenotypic profiling of replicative-senescent human foreskin fibroblasts under brief heat shock.Cell stress & chaperones · 2026Article
- Heat stress-mediated oxidative damage in male germ cells: potential protective effects of L-citrulline.Frontiers in endocrinology · 2026Review
- Heat Shock Response and Heat Shock Proteins: Current Understanding and Future Opportunities in Human Diseases.International journal of molecular sciences · 2024Review
- Heat shock protein 70 (HmHsp70) from Hypsizygus marmoreus confers thermotolerance to tobacco.AMB Express · 2020Article
- The Potential Link between Thermal Resistance and Virulence inFrontiers in veterinary science · 2017Review
- Performance of a Heating Block System Designed for Studying the Heat Resistance of Bacteria in Foods.Scientific reports · 2016Article
- Article
- Structural basis for intrinsic thermosensing by the master virulence regulator RovA of Yersinia.The Journal of biological chemistry · 2012Article
- Concerted actions of a thermo-labile regulator and a unique intergenic RNA thermosensor control Yersinia virulence.PLoS pathogens · 2012Article
- Comparative transcriptional analysis of clinically relevant heat stress response in Clostridium difficile strain 630.PloS one · 2012Article
- PIPS: pathogenicity island prediction software.PloS one · 2012Article
- Article
- Gene-centric association analysis for the correlation between the guanine-cytosine content levels and temperature range conditions of prokaryotic species.BMC bioinformatics · 2010Article
- Microbial thermosensors.Cellular and molecular life sciences : CMLS · 2009Review
- Intrinsic thermal sensing controls proteolysis of Yersinia virulence regulator RovA.PLoS pathogens · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Temperature is an important physical stress factor sensed by bacteria and used to regulate gene expression. Three different macromolecules have been identified being able to sense temperature: DNA, mRNA and proteins. Depending on the induction mechanism, two different pathways have to be distinguished, namely the heat shock response and the high temperature response. While the heat shock response is induced by temperature increments and is transient, the high temperature response needs a specific temperature to become induced and proceeds as long as cells are exposed to that temperature. The heat shock response is induced by denatured proteins and aimed to prevent formation of protein aggregates by refolding or degradation, and the high temperature response is mainly used by pathogenic bacteria to detect entry into a mammalian host followed by induction of their virulence genes. All known high temperature sensors are present in two alternative conformations depending on the temperature. Heat shock sensors are either molecular chaperones or proteases which keep either a positive transcriptional regulator inactive or a negative regulator active or do not attack the regulator, respectively, under physiological conditions. Denatured proteins either titrate the molecular chaperones or activate the protease. The evolution of the different temperature sensors is discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.