ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2007
Mapping QTLs with digenic epistasis under multiple environments and predicting heterosis based on QTL effects.
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Modification of Experimental Design and Statistical Method for Mapping Imprinted QTLs Based on Immortalized FFrontiers in genetics · 2020Article
- Genetic dissection of yield-related traits and mid-parent heterosis for those traits in maize (Zea mays L.).BMC plant biology · 2019Article
- Detection and characterization of epistasis between QTLs on plant height in rice using single segment substitution lines.Breeding science · 2015Article
- Statistical method for mapping QTLs for complex traits based on two backcross populations.Chinese science bulletin = Kexue tongbao · 2012Article
- Dynamic analysis of QTLs on tiller number in rice (Oryza sativa L.) with single segment substitution lines.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2012Article
- Phenotyping for drought tolerance of crops in the genomics era.Frontiers in physiology · 2012Article
- A new mapping method for quantitative trait loci of silkworm.BMC genetics · 2011Article
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Authors and funding
2 authors.
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Abstract
Mixed linear model approach was proposed for mapping QTLs with the digenic epistasis and QTL by environment (QE) interaction as well as additive and dominant effects. Monte Carlo simulations indicated that the proposed method could provide unbiased estimations for both positions and genetic main effects of QTLs, as well as unbiased predictions for QE interaction effects. A method was suggested for predicting heterosis based on individual QTL effects. The immortalized F(2) (IF(2)) population constructed by random mating among RI or DH lines is appropriate for mapping QTLs with epistasis and their QE interaction. Based on the models and methodology proposed, we developed a QTL mapping software, QTLMapper 2.0 on the basis of QTLmapper 1.0, which is suitable for analyzing populations of DH, RIL, F(2) and IF(2). Data of thousand grain weight of IF(2) population with 240 lines derived from elite hybrid rice Shanyou 63 were analyzed as a worked example.
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