SynthesisPediatrics2007
Adherence to antiretroviral therapy for pediatric HIV infection: a qualitative systematic review with recommendations for research and clinical management.
Synthesis in Pediatrics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
104 citing papers in PubMed, 11 syntheses or guidelines pooled it, 221 citations in OpenAlex.
- Interventions to enhance HIV medication adherence among individuals using substances: a systematic review and critique of the literature.AIDS care · 2026Pooled it
- What leads to treatment failure among people living with HIV: first systematic review from the middle east and North Africa.Virology journal · 2025Pooled it
- Family Influences on Antiretroviral Therapy Adherence in Youth with HIV in the United States: A Systematic Review.AIDS and behavior · 2025Pooled it
- Pooled it
- Social and Structural Determinants of Household Support for ART Adherence in Low- and Middle-Income Countries: A Systematic Review .International journal of environmental research and public health · 2020Pooled it
- Adherence to Highly Active Antiretroviral Therapy Among Children in Ethiopia: A Systematic Review and Meta-analysis.AIDS and behavior · 2018Pooled it
- Paediatric European Network for Treatment of AIDS (PENTA) guidelines for treatment of paediatric HIV-1 infection 2015: optimizing health in preparation for adult life.HIV medicine · 2018Guideline
- Identification of evidence-based interventions for promoting HIV medication adherence: findings from a systematic review of U.S.-based studies, 1996-2011.AIDS and behavior · 2014Pooled it
- The impact of specific HIV treatment-related adverse events on adherence to antiretroviral therapy: a systematic review and meta-analysis.AIDS care · 2013Pooled it
- Interventions to improve adherence to antiretroviral therapy in children with HIV infection.The Cochrane database of systematic reviews · 2011Pooled it
- Evidence-based gender findings for children affected by HIV and AIDS - a systematic overview.AIDS care · 2009Pooled it
- A Longitudinal Analysis of Antiretroviral Adherence Among Young Black Men Who Have Sex With Men.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2017Trial
- Effect of an Empowerment Intervention on Antiretroviral Drug Adherence in Thai Youth.Behavioral medicine (Washington, D.C.) · 2015Trial
- Short message service (SMS)-based intervention to improve treatment adherence among HIV-positive youth in Uganda: focus group findings.PloS one · 2015Trial
- Multisystemic therapy for poorly adherent youth with HIV: results from a pilot randomized controlled trial.AIDS care · 2013Trial
- Trial
- Adherence to isoniazid prophylaxis among HIV-infected children: a randomized controlled trial comparing two dosing schedules.BMC medicine · 2009Trial
- Effect of Process and Formulation Variables on Quality, Stability, and Taste of Lamivudine Printlets Manufactured by Binder Jetting 3D Printing Method.AAPS PharmSciTech · 2026Article
- Viral Response among Early Treated HIV Perinatally Infected Infants: Description of a Cohort in Southern Mozambique.Healthcare (Basel, Switzerland) · 2022Article
- Effect of alcohol exposure on the efficacy and safety of tenofovir alafenamide fumarate, a major medicine against human immunodeficiency virus.Biochemical pharmacology · 2022Article
44 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 5 institutions in 1 country.
Funding
Abstract
Although nonadherence to prescribed therapies is widespread, it is particularly problematic with highly active antiretroviral therapy for HIV infection. This review of >50 studies in the area of pediatric HIV infection revealed varying methods for assessing antiretroviral adherence with a wide range of estimates of adherence. Correlates of adherence could be grouped as those relating to the medication, the patient, and the caregiver/family, with many conflicting findings and a lack of theory guiding the research. Only 8 studies, mainly small feasibility or pilot investigations, evaluated highly active antiretroviral therapy adherence interventions in pediatric populations. We conclude with specific recommendations for assessment and clinical management of adherence and discuss directions for future research in this area.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.