Evidence map›Paper›PMID 17531262›Full record

ReviewJournal of molecular and cellular cardiology2007

Kruppel-like Factors (KLFs) in muscle biology.

Saptarsi M Haldar, Osama A Ibrahim, Mukesh K Jain

Open access · greenAbstract readReview
In one paragraph

Review in Journal of molecular and cellular cardiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 92 citations in OpenAlex.

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  5. Genome-Wide Identification, Evolution, and miRNA-22 Regulation ofAnimals : an open access journal from MDPI · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Saptarsi M HaldarCase Cardiovascular Research Institute, Case Western Reserve University School of Medicine and University Hospitals of Cleveland / Case Medical Center, Cleveland, OH 44106, USA.
Osama A Ibrahim
Mukesh K Jain
Case Western Reserve University · US

Funding

KLF2, monocyte activation and vascular inflammationR01HL086548 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI JAIN, MUKESH KUMAR · 2007 to 2016
$3.5M
KLF2 as a regulator of endothelial cell biologyR01HL076754 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI JAIN, MUKESH KUMAR · 2004 to 2012
$3.2M
KLF4, Monocyte Biology and Vasculary InjuryR01HL075427 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI JAIN, MUKESH KUMAR · 2004 to 2010
$2.6M
KLF15 as novel regulator of cardiomyocyte biologyR01HL084154 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI JAIN, MUKESH KUMAR · 2007 to 2010
$1.5M
KLF15, TGFb1 and smooth muscle cell biologyR01HL072952 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI JAIN, MUKESH KUMAR · 2004 to 2007
$1.5M
NHLBI NIH HHS R01 HL072952NHLBI NIH HHS R01 HL075427NHLBI NIH HHS R01 HL076754NHLBI NIH HHS R01 HL084154NHLBI NIH HHS R01 HL086548
6 · The paper itself

Abstract

The Kruppel-like Factor (KLF) family of zinc-finger transcription factors are critical regulators of cell differentiation, phenotypic modulation and physiologic function. An emerging body of evidence implicates an important role for these factors in cardiovascular biology, however, the role of KLFs in muscle biology is only beginning to be understood. This article reviews the published data describing the role of KLFs in the heart, smooth muscle, and skeletal muscle and highlights the importance of these factors in cardiovascular development, physiology and disease pathobiology.

Indexed as

Muscle, SkeletalMuscle, SmoothMyocardiumCardiovascular DiseasesHumansKruppel-Like Transcription FactorsKruppel-Like Transcription Factors

Identifiers

PMID17531262
PMCPMC2743293
OpenAlexW2004496629

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.