Evidence map›Paper›PMID 17530803›Full record

ArticleThe Journal of organic chemistry2007

Synthesis of aza-analogues of the glycosylated tyrosine portion of mannopeptimycin-E.

Sanjeeva R Guppi, George A O'Doherty

Abstract read
In one paragraph

Article in The Journal of organic chemistry, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sanjeeva R GuppiDepartment of Chemistry, West Virginia University, Morgantown, West Virginia 26506, USA.
George A O'Doherty

Funding

Synthesis of Papulacandins A-D;New Antifungal AnalogsR01GM063150 · NIGMS · WEST VIRGINIA UNIVERSITY · PI O'DOHERTY, GEORGE A · 2002 to 2005
$986k
NIGMS NIH HHS GM63150NIGMS NIH HHS R01 GM063150
6 · The paper itself

Abstract

Two C4' amido disaccharide analogues of mannopeptimycin-E were synthesized via an iterative palladium glycosylation sequence. The stereoselective synthesis of the C4' acylated 1,4-alpha,alpha-manno,manno-amido disaccharide has been achieved in ten steps from a protected d-tyrosine. The path relies upon a regio- and diastereoselective palladium-catalyzed azide substitution reaction. The competence of the synthesis is demonstrated by the good overall yield (21%) from protected tyrosine.

Indexed as

Allyl CompoundsAmidesAminesAza CompoundsDisaccharidesGlycopeptidesGlycosylationMolecular StructureOxygenTyrosineAllyl CompoundsAmidesAminesAza CompoundsDisaccharidesGlycopeptidesmannopeptimycin-EOxygenTyrosine

Identifiers

PMID17530803
PMCPMC2546506

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.