Evidence map›Paper›PMID 17526756›Full record

ArticleAntimicrobial agents and chemotherapy2007

Sequencing and comparative genomic analysis of pK29, a 269-kilobase conjugative plasmid encoding CMY-8 and CTX-M-3 beta-lactamases in Klebsiella pneumoniae.

Ying-Tsong Chen, Tsai-Ling Lauderdale, Tsai-Lien Liao, Yih-Ru Shiau, Hung-Yu Shu, Keh-Ming Wu, Jing-Jou Yan, Ih-Jen Su, Shih-Feng Tsai

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Article
  3. Class C β-Lactamases: Molecular Characteristics.Clinical microbiology reviews · 2022
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  17. Aminoglycoside modifying enzymes.Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2010
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ying-Tsong ChenDivision of Molecular and Genomic Medicine, National Health Research Institutes, Zhunan Town, Miaoli County 350, Taiwan. onion@nhri.org.tw
Tsai-Ling Lauderdale
Tsai-Lien Liao
Yih-Ru Shiau
Hung-Yu Shu
Keh-Ming Wu
Jing-Jou Yan
Ih-Jen Su
Shih-Feng Tsai
National Health Research Institutes · TWNational Yang Ming Chiao Tung University · TWNational Cheng Kung University Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 269-kilobase conjugative plasmid, pK29, from a Klebsiella pneumoniae strain was sequenced. The plasmid harbors multiple antimicrobial resistance genes, including those encoding CMY-8 AmpC-type and CTX-M-3 extended-spectrum beta-lactamases in the common backbone of IncHI2 plasmids. Mechanisms for dissemination of the resistance genes are highlighted in comparative genomic analyses.

Indexed as

Conjugation, GeneticGenomicsSequence Analysis, DNAAnti-Bacterial Agentsbeta-Lactamasesbeta-Lactam ResistanceHumansKlebsiella pneumoniaeMicrobial Sensitivity TestsMolecular Sequence DataPlasmidsAnti-Bacterial Agentsbeta-lactamase CTX-M-3beta-Lactamases

Identifiers

PMID17526756
PMCPMC1932545
OpenAlexW2099953296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.