Evidence map›Paper›PMID 17526577›Full record

ArticleBiophysical journal2007

Effects of cholesterol on dry bilayers: interactions between phosphatidylcholine unsaturation and glycolipid or free sugar.

Antoaneta V Popova, Dirk K Hincha

Open access · bronzeAbstract read
In one paragraph

Article in Biophysical journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 59 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Antoaneta V PopovaMax-Planck-Institut für Molekulare Pflanzenphysiologie, D-14424 Potsdam, Germany.
Dirk K Hincha
Max Planck Institute of Molecular Plant Physiology · DEMax Planck Society · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholesterol and other sterols are important components of biological membranes and are known to strongly influence the physical characteristics of lipid bilayers. Although this has been studied extensively in fully hydrated membranes, little is known about the effects of cholesterol on the stability of membranes in the dry state. Here, we present a Fourier transform infrared spectroscopy study on the effects of cholesterol on the phase behavior of dry liposomes composed of phosphatidylcholines with different degrees of fatty acid unsaturation or of mixtures of phosphatidylcholine with a plant galactolipid. In addition, we have analyzed the H-bonding of cholesterol, galactose, and a combination of the two additives to the P=O and C=O groups in dry phosphatidylcholine bilayers. The data indicate a complex balance of interactions between the different components in the dry state and a strong influence of fatty acid unsaturation on the interactions of the diacyl lipids with both cholesterol and galactose.

Indexed as

CholesterolFatty Acids, UnsaturatedGalactolipidsGalactoseGlycolipidsHydrogen BondingLipid BilayersLiposomesPhase TransitionPhosphatidylcholinesSpectroscopy, Fourier Transform InfraredWaterCholesteroldigalactosyldiacylglycerolFatty Acids, UnsaturatedGalactolipidsGalactoseGlycolipidsLipid BilayersLiposomesPhosphatidylcholinesWater

Identifiers

PMID17526577
PMCPMC1929023
OpenAlexW2058084946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.