ArticleIntensive care medicine2007
Agreement of central venous saturation and mixed venous saturation in cardiac surgery patients.
Article in Intensive care medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.
- Estimating Coronary Sinus Oxygen Saturation from Pulmonary Artery Oxygen Saturation.Medicina (Kaunas, Lithuania) · 2024Pooled it
- [The pulmonary artery catheter-Not a niche tool but often a must].Die Anaesthesiologie · 2026Review
- Correlation between central venous oxygen saturation and mixed venous oxygen saturation in surgical patients: A systematic review and meta-analysis.Annals of intensive care · 2026Review
- One approach to circulation and blood flow in the critical care unit.World journal of critical care medicine · 2019Review
- [Hemodynamic target variables in the intensive care unit].Der Anaesthesist · 2018Article
- [Venous saturation : Between oxygen delivery and consumption].Medizinische Klinik, Intensivmedizin und Notfallmedizin · 2017Review
- High central venous saturation after cardiac surgery is associated with increased organ failure and long-term mortality: an observational cross-sectional study.Critical care (London, England) · 2015Observational
- [Cerebral oximetry: clinical importance for cardiac surgery patients].Der Anaesthesist · 2012Review
- Clinical review: use of venous oxygen saturations as a goal - a yet unfinished puzzle.Critical care (London, England) · 2011Review
- No agreement of mixed venous and central venous saturation in sepsis, independent of sepsis origin.Critical care (London, England) · 2010Article
- [Haemodynamic monitoring in the perioperative phase. Available systems, practical application and clinical data].Der Anaesthesist · 2009Review
- Letter to the editor regarding the paper "Agreement of central venous saturation and mixed venous saturation in cardiac surgery patients by Sander M, Spies CD, Foer A, Weymann L, Braun J, Volk T, Grubitzsch H, von Heymann C (2007) Intensive Care Medicine 33:1719-1725".Intensive care medicine · 2008Article
- Central venous to mixed venous blood oxygen and lactate gradients are associated with outcome in critically ill patients.Intensive care medicine · 2008Article
- Year in review in Intensive Care Medicine, 2007. II. Haemodynamics, pneumonia, infections and sepsis, invasive and non-invasive mechanical ventilation, acute respiratory distress syndrome.Intensive care medicine · 2008Review
- Year in review 2007: Critical Care--cardiology.Critical care (London, England) · 2008Review
- Role of central venous - Arterial pCO2 difference in determining microcirculatory hypoperfusion in off-pump coronary artery bypass grafting surgery.Annals of cardiac anaesthesiaObservational
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveComparison of the bias and the limits of agreement (LOA; 2 SD) of the central venous saturation (S(cv)O(2)) before, during and after coronary artery bypass graft surgery with a simultaneous measurement of the mixed venous saturation (S(v)O(2)). DESIGN AND
settingProspective controlled study in a university hospital department of anaesthesiology. PATIENTS: 60 patients with coronary artery bypass surgery, 300 paired measurements of S(v)O(2) and S(cv)O(2). MEASUREMENTS AND
resultsS(cv)O(2) and S(v)O(2) were analysed after induction of anaesthesia 15 min after cardiopulmonary bypass and 1, 6 and 18 h after admission to the intensive care unit. Regression analysis for the pooled measurements of S(cv)O(2) and S(v)O(2) showed a correlation R (2) = 0.52. After induction of anaesthesia 15 min after weaning from cardiopulmonary bypass and 6 h after admission to the intensive care unit the correlation coefficient was R (2) = 0.46, on admission to the intensive care unit it was R (2) = 0.42, and at 18 h it was R (2) = 0.38. Bland-Altman analysis for the measurements of S(cv)O(2) and S(v)O(2) showed a mean bias and LOA of 0.3% and -11.9 to +12.4%. In patients with a low S(cv)O(2) there was a trend to overestimate the S(v)O(2) by using the S(cv)O(2). The only factor that influenced the DeltaS(v)O(2) - S(cv)O(2) was the oxygen extraction rate (R (2) = 0.16). In patients with S(cv)O(2) below 70% this association was more pronounced (R (2) = 0.60).
conclusionsOur findings demonstrate that oxygen extraction rate is the major factor in the difference between S(v)O(2) and S(cv)O(2). Under certain circumstances S(cv)O(2) differed substantially from S(v)O(2). Therefore in selected patients both parameters should be monitored to exclude general or focal hypoperfusion.
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