ArticlePLoS clinical trials2007
A cluster randomized clinical trial to improve prescribing patterns in ambulatory pediatrics.
Article in PLoS clinical trials, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Interventions to reduce inappropriate prescribing of antibiotics for acute respiratory tract infections: summary and update of a systematic review.The Journal of international medical research · 2018Pooled it
- Effects of computer-aided clinical decision support systems in improving antibiotic prescribing by primary care providers: a systematic review.Journal of the American Medical Informatics Association : JAMIA · 2015Pooled it
- Computerized clinical decision support systems for acute care management: a decision-maker-researcher partnership systematic review of effects on process of care and patient outcomes.Implementation science : IS · 2011Pooled it
- Computerized clinical decision support systems for drug prescribing and management: a decision-maker-researcher partnership systematic review.Implementation science : IS · 2011Pooled it
- Do computerised clinical decision support systems for prescribing change practice? A systematic review of the literature (1990-2007).BMC health services research · 2009Pooled it
- The effects of on-screen, point of care computer reminders on processes and outcomes of care.The Cochrane database of systematic reviews · 2009Pooled it
- Features predicting the success of computerized decision support for prescribing: a systematic review of randomized controlled trials.BMC medical informatics and decision making · 2009Pooled it
- The effectiveness of integrated health information technologies across the phases of medication management: a systematic review of randomized controlled trials.Journal of the American Medical Informatics Association : JAMIAPooled it
- Antibiotic clinical decision support for pneumonia in the ED: A randomized trial.Journal of hospital medicine · 2023Trial
- Process evaluation of a point-of-care cluster randomised trial using a computer-delivered intervention to reduce antibiotic prescribing in primary care.BMC health services research · 2014Trial
- Interventions to Minimize Unnecessary Antibiotic Use for Acute Otitis Media: A Meta-Analysis.Children (Basel, Switzerland) · 2025Review
- Development and assessment of an online communication skills course to optimise antibiotic prescribing for children in primary care.BMC primary care · 2025Article
- Impact of Point-of-Care Decision Support Tool on Laboratory Screening for Comorbidities in Children with Obesity.Children (Basel, Switzerland) · 2020Article
- Improved antibiotic prescribing using indication-based clinical decision support in the emergency department.Journal of the American College of Emergency Physicians open · 2020Article
- Using Clinical Decision Support Within the Electronic Health Record to Reduce Incorrect Prescribing for Acute Sinusitis.Journal of patient-centered research and reviews · 2018Article
- Health information technology adoption in U.S. acute care hospitals.Journal of medical systems · 2013Article
- Effectiveness of physician-targeted interventions to improve antibiotic use for respiratory tract infections.The British journal of general practice : the journal of the Royal College of General Practitioners · 2012Review
- Developing a computer delivered, theory based intervention for guideline implementation in general practice.BMC family practice · 2010Article
- Effectiveness of electronic guideline-based implementation systems in ambulatory care settings - a systematic review.Implementation science : IS · 2009Article
- Computerized clinical decision support for medication prescribing and utilization in pediatrics.Journal of the American Medical Informatics Association : JAMIAReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
objectivesHaving shown previously that an electronic prescription writer and decision support system improved pediatric prescribing behavior for otitis media in an academic clinic setting, we assessed whether point-of-care delivery of evidence could demonstrate similar effects for a wide range of other common pediatric conditions.
designCluster randomized controlled trial.
settingA teaching clinic/clinical practice site and a primary care pediatric clinic serving a rural and semi-urban patient mix.
participantsA total of 36 providers at the teaching clinic/practice site and eight providers at the private primary pediatric clinic.
interventionAn evidence-based message system that presented real-time evidence to providers based on prescribing practices for acute otitis media, allergic rhinitis, sinusitis, constipation, pharyngitis, croup, urticaria, and bronchiolitis. OUTCOME MEASURES: The proportion of prescriptions dispensed in accordance with evidence.
resultsThe proportion of prescriptions dispensed in accordance with evidence improved four percentage points, from 38% at baseline to 42% following the intervention. The control group improved by one percentage point, from 39% at baseline to 40% at trial's conclusion. The adjusted difference between the intervention and control groups was 8% (95% confidence interval 1%, 15%). Intervention effectiveness did not decrease with time.
conclusionFor common pediatric outpatient conditions, a point-of-care evidence-based prescription writer and decision support system was associated with significant improvements in prescribing practices.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.