Evidence map›Paper›PMID 17525109›Full record

ArticleThe Journal of physiology2007

Setting up for the block: the mechanism underlying lidocaine's use-dependent inhibition of sodium channels.

Theodore R Cummins

Abstract readComment
In one paragraph

Article in The Journal of physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Trial
  2. Continuous infusion of lidocaine in pediatric colonoscopy: A randomized double-blind placebo-controlled study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Trial
  3. Observational
  4. Article
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. Protein 14-3-3 Influences the Response of the Cardiac Sodium Channel NaThe Journal of pharmacology and experimental therapeutics · 2023
    Article
  12. Review
  13. Article
  14. Treatment and diagnosis of chemotherapy-induced peripheral neuropathy: An update.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Theodore R CumminsDepartment of Pharmacology and Toxicology, Stark Neurosciences Research Institute, Indiana University School of Medicine, 950 W. Walnut St, R2-Room 468, Indianapolis, IN 46202, USA . rcummin@iupui.edu

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anesthetics, LocalAnti-Arrhythmia AgentsArginineBinding SitesBiotinCell LineCysteineHumansIon Channel GatingKineticsLidocaineMembrane PotentialsMuscle ProteinsMutationNAV1.5 Voltage-Gated Sodium ChannelProtein ConformationAnesthetics, LocalAnti-Arrhythmia AgentsArginineBiotinCysteineLidocaineMuscle ProteinsNAV1.5 Voltage-Gated Sodium ChannelN-biotinylaminoethyl methanethiosulfonateSCN5A protein, humanSodium Channel BlockersSodium Channels

Identifiers

PMID17525109
PMCPMC2075285

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.