Evidence map›Paper›PMID 17524744›Full record

ReviewThe American journal of medicine2007

Direct-to-consumer advertising of pharmaceuticals.

Ziad F Gellad, Kenneth W Lyles

Abstract readReview
In one paragraph

Review in The American journal of medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Advertisements impact the physiological efficacy of a branded drug.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Trial
  6. Trial
  7. Amphetamines: a current epidemic.Frontiers in psychiatry · 2025
    Article
  8. Article
  9. Improving the reach of clinical practice guidelines: An experimental investigation of message framing on user engagement.Clinical psychological science : a journal of the Association for Psychological Science · 2020
    Article
  10. Article
  11. The Main Factors of Induced Demand for Medicine Prescription: A Qualitative Study.Iranian journal of pharmaceutical research : IJPR · 2019
    Article
  12. Article
  13. Direct to consumer advertising on websites of Peruvian naturopathic pharmacies.European journal of hospital pharmacy : science and practice · 2017
    Article
  14. Article
  15. Direct-to-Consumer Prescription Medicine Advertising and Seniors' Knowledge of Alzheimer's Disease.American journal of Alzheimer's disease and other dementias · 2016
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ziad F GelladDivision of Gastroenterology, Duke University Medical Center, Durham, NC 27710, USA. z.gellad@duke.edu
Kenneth W Lyles

Funding

Resource Core 3 - Metabolomics CoreP30AG028716 · NIA · DUKE UNIVERSITY · PI CATHLEEN S COLON-EMERIC · 2006 to 2026
$24.6M
NIA NIH HHS P30 AG028716
6 · The paper itself

Abstract

Since the US Food and Drug Administration (FDA) released new guidelines on broadcast direct-to-consumer advertising in 1997, the prevalence of direct-to-consumer advertising of prescription drugs has increased exponentially. The impact on providers, patients, and the health care system is varied and dynamic, and the rapid changes in the last several years have markedly altered the health care landscape. To continue providing optimal medical care, physicians and other health care providers must be able to manage this influence on their practice, and a more thorough understanding of this phenomenon is an integral step toward this goal. This review will summarize the history of direct-to-consumer drug advertisements and the current regulations governing them. It will summarize the evidence concerning the impact of direct-to-consumer advertising on the public, providers, and the health care system, and conclude with observations regarding the future of direct-to-consumer advertising.

Indexed as

AdvertisingCommunity ParticipationDrug PrescriptionsEconomics, PharmaceuticalHumansPatient Education as TopicPhysician-Patient Relations

Identifiers

PMID17524744
PMCPMC3967783

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.