ArticleClinical oral investigations2007
Antifungal susceptibility of Candida albicans biofilms on titanium discs with different surface roughness.
Article in Clinical oral investigations, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- The antifungal and antibiofilm activity of Cymbopogon nardus essential oil and citronellal on clinical strains of Candida albicans.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2022Article
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- The Effectiveness of Chlorhexidine and Air Polishing System in the Treatment ofAntibiotics (Basel, Switzerland) · 2020Article
- Article
- Critical physiological factors influencing the outcome of antimicrobial testing according to ISO 22196 / JIS Z 2801.PloS one · 2018Article
- Evaluation ofThe journal of advanced prosthodontics · 2017Article
- Electro-chemical deposition of nano hydroxyapatite-zinc coating on titanium metal substrate.International journal of implant dentistry · 2017Article
- Biofilm Analysis of Retrieved Dental Implants after Different Peri-Implantitis Treatments.Case reports in dentistry · 2017Article
- Thickness Influence onMaterials (Basel, Switzerland) · 2016Article
- Inhibition of adherence of C. albicans to dental implants and cover screws by Cymbopogon nardus essential oil and citronellal.Clinical oral investigations · 2015Article
- Biofilm Formation and Susceptibility to Amphotericin B and Fluconazole in Candida albicans.Jundishapur journal of microbiology · 2014Article
- Antibacterial properties and human gingival fibroblast cell compatibility of TiO2/Ag compound coatings and ZnO films on titanium-based material.Clinical oral investigations · 2012Article
- XTT assay of ex vivo saliva biofilms to test antimicrobial influences.GMS Krankenhaushygiene interdisziplinar · 2012Article
- Salivary proteins as predictors and controls for oral health.Journal of cell communication and signaling · 2011Article
- Candida albicans adhesion to composite resin materials.Clinical oral investigations · 2009Article
- The oral cavity--a key system to understand substratum-dependent bioadhesion on solid surfaces in man.Clinical oral investigations · 2009Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although it is well known that fungal biofilms have increased resistance to antimicrobial agents, limited information is available on the formation of candidal biofilms on implant surfaces with different surface roughness and their resistance to conventional antifungal therapy. In the current study, the effect of increasing the surface roughness of titanium discs on the susceptibility of Candida albicans biofilms to amphotericin B was determined. Grade I commercially pure titanium discs were sandblasted with 99.6% aluminium oxide of different grit sizes, producing surface roughness of 0.90, 1.88 and 3.82 microm (Groups A, B and C), respectively (P < 0.001). The antifungal susceptibility of C. albicans biofilm grown on different Ti discs was determined using XTT assay. The 50% reduction in metabolic activity (50% RMA) of planktonic C. albicans (0.5 microg/mL) was much lower than those from Groups A, B and C (2, 16, 2 microg/mL, respectively), while the 50% RMA from Group B was three-fold higher than those from Groups A and C. In conclusion, difference in titanium surface roughness was associated with variations in the antifungal resistance of the candidal biofilm. Group C appeared to have an optimum surface roughness for biofilm resistance.
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