SynthesisNeurocritical care2007
Role of intracranial pressure values and patterns in predicting outcome in traumatic brain injury: a systematic review.
Synthesis in Neurocritical care, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05593380 (The Impact of Invasive Intracranial Pressure Monitoring Guided Management on the Functional Outcomes of Patients With Supratentorial Large Volume Cerebral Hemorrhage), which is not on this map. Cited by 82 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Impact of Invasive Intracranial Pressure Monitoring Guided Management on the Functional Outcomes of Patients With Supratentorial Large Volume Cerebral Hemorrhage: An Open Label, Randomized, Controlled, Multi-center Trial (BIATICH)
Who cites it
82 citing papers in PubMed, 5 syntheses or guidelines pooled it, 220 citations in OpenAlex.
- Guidelines for the Acute Treatment of Cerebral Edema in Neurocritical Care Patients.Neurocritical care · 2020Guideline
- Hypertonic saline versus other intracranial pressure-lowering agents for people with acute traumatic brain injury.The Cochrane database of systematic reviews · 2020Pooled it
- Hypertonic saline versus other intracranial pressure-lowering agents for people with acute traumatic brain injury.The Cochrane database of systematic reviews · 2019Pooled it
- Pooled it
- Consensus summary statement of the International Multidisciplinary Consensus Conference on Multimodality Monitoring in Neurocritical Care : a statement for healthcare professionals from the Neurocritical Care Society and the European Society of Intensive Care Medicine.Intensive care medicine · 2014Guideline
- Trial
- Estimate the severity of acute ischemic stroke by optic nerve sheath ultrasound.The ultrasound journal · 2025Article
- Unlocking therapeutic potential in traumatic brain injury: exploring microenvironmental targets, signaling pathways and translational hurdles.Inflammopharmacology · 2025Review
- Early Positive Fluid Balance Associates with Increased Mortality in Neurological Critically Ill Patients: A 10-Year Cohort Study.Journal of clinical medicine · 2025Article
- Development and Validation of a Neurological Outcome Prediction Score for Children Requiring Mechanical Ventilation: The NOPS-VC Score.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025Article
- Hypertension, blood-brain barrier disruption and changes in intracranial pressure.The Journal of physiology · 2025Review
- Optical approaches for neurocritical care: Toward non-invasive recording of cerebral physiology in acute brain injury.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025Review
- Impact of Craniectomy Size on Outcomes in Traumatic Brain Injury: A Retrospective Study at Shohadaye-Haftome-Tir Hospital, Tehran, Iran (2019-2021).Medical journal of the Islamic Republic of Iran · 2025Article
- "NeuroVanguard": a contemporary strategy in neuromonitoring for severe adult brain injury patients.Critical care (London, England) · 2024Review
- The potential role of mechanotransduction in the management of pediatric calvarial bone flap repair.Biotechnology and bioengineering · 2024Review
- Intracranial and Blood Pressure Variability and In-Hospital Outcomes in Intracranial Device-Monitored Patients with Spontaneous Intracerebral Hemorrhage.Neurocritical care · 2023Article
- Comparison of intracranial pressure prediction in hydrocephalus patients among linear, non-linear, and machine learning regression models in Thailand.Acute and critical care · 2023Article
- Accuracy of Manual Intracranial Pressure Recording Compared to a Computerized High-Resolution System: A CENTER-TBI Analysis.Neurocritical care · 2023Article
- Non-Invasive Intracranial Pressure Monitoring.Journal of clinical medicine · 2023Review
- Ultrasonographic measurement of the optic nerve sheath diameter to detect intracranial hypertension: an observational study.The ultrasound journal · 2023Article
22 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionRaised intracranial pressure (ICP) has been consistently associated with poor neurological outcome. Our purpose was to systematically review the literature to estimate the association between ICP values and patterns and short- and long-term vital and neurological outcome.
methodsSystematic review of studies identified from MEDLINE, EMBASE, and COCHRANE Registry search from 1966 to 2005, and reference lists of identified articles, with independent assessment of methodological quality, population, ICP values and patterns, management of raised ICP and neurological outcomes. Summary odds ratios (OR) were calculated for the main outcomes using proportional odds models and logistic regression.
resultsFour prospective studies (409 patients) reported the effect of ICP values, and five studies (677 patients) reported the effect of ICP patterns on neurological outcome. No study reported neurological outcomes beyond 1 year. Relative to normal ICP (<20 mmHg), raised ICP was associated with elevated OR of death: 3.5 [95%CI: 1.7, 7.3] for ICP 20-40, and 6.9 [95%CI: 3.9, 12.4] for ICP>40. Raised but reducible ICP was associated with a 3-4-fold increase in the OR of death or poor neurological outcome. Refractory ICP pattern was associated with a dramatic increase in the relative risk of death (OR 114.3 [95%CI: 40.5, 322.3]).
conclusionsRefractory ICP and response to treatment of raised ICP could be better predictors of neurological outcome than absolute ICP values. Limitations in the design of the studies analyzed precluded identification of the role of ICP monitoring in predicting short- and long-term outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.