ArticleInternational ophthalmology2007
Bilateral orbital myeloid sarcoma as initial manifestation of acute myeloid leukemia.
Article in International ophthalmology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 19 citations in OpenAlex.
- Atypical orbital mass as the precursor for myelodysplastic syndrome recurrence: a case report.American journal of ophthalmology case reports · 2025Article
- Myeloid Sarcoma Presenting as Brain Tumor in Pediatric Acute Myeloid Leukemia Case.Turkish archives of pediatrics · 2023Article
- Epidemiological Trends and Clinical Characteristics of Childhood Leukemia in Saudi Arabia: A Review.Cureus · 2022Review
- Article
- Clinical and genomic features of adult and paediatric acute leukaemias with ophthalmic manifestations.BMJ open ophthalmology · 2019Article
- Orbital myeloid sarcoma in adult mimicking nasolacrimal duct obstruction: A case report.American journal of ophthalmology case reports · 2016Article
- Unilateral eyelid swelling, proptosis and diplopia as initial manifestation of acute myeloid leukemia.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society · 2012Article
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGranulocytic sarcoma is a rare orbital complication of acute leukemia. It concerns primarily children under 10 years of age suffering from primitive acute myeloid leukemia. The diagnosis is made by clinical examination, computed tomography and confirmed by haematological investigations. The treatment approach is based on chemotherapy associated with intravenous steroid therapy. CASE REPORT: We report the case of a 6-year-old girl who presented with bilateral proptosis revealing acute myeloid leukemia. The patient was treated by a combination of chemotherapeutic drugs in two phases, associated with intravenous steroids. After a follow-up period of 24 months, the patient was in complete remission.
conclusionThe diagnosis of granulocytic sarcoma should be considered in any orbital mass of uncertain origin, particularly if it is bilateral. Special stains and immunohistochemistry play an important role in the diagnosis.
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