ArticleEuropean journal of clinical nutrition2008
Effects of a short-term intervention with a paleolithic diet in healthy volunteers.
Article in European journal of clinical nutrition, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 5 syntheses or guidelines pooled it, 172 citations in OpenAlex.
- The Relationship between Modern Fad Diets and Kidney Stone Disease: A Systematic Review of Literature.Nutrients · 2021Pooled it
- Pooled it
- Influence of Paleolithic diet on anthropometric markers in chronic diseases: systematic review and meta-analysis.Nutrition journal · 2019Pooled it
- Effects of a Paleolithic Diet on Cardiovascular Disease Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Advances in nutrition (Bethesda, Md.) · 2019Pooled it
- Paleolithic nutrition for metabolic syndrome: systematic review and meta-analysis.The American journal of clinical nutrition · 2015Pooled it
- Trial
- A Modified MCT-Based Ketogenic Diet Increases Plasma β-Hydroxybutyrate but Has Less Effect on Fatigue and Quality of Life in People with Multiple Sclerosis Compared to a Modified Paleolithic Diet: A Waitlist-Controlled, Randomized Pilot Study.Journal of the American College of Nutrition · 2021Trial
- A Paleolithic diet lowers resistant starch intake but does not affect serum trimethylamine-N-oxide concentrations in healthy women.The British journal of nutrition · 2019Trial
- Trial
- Metabolic and physiologic effects from consuming a hunter-gatherer (Paleolithic)-type diet in type 2 diabetes.European journal of clinical nutrition · 2015Trial
- Favourable effects of consuming a Palaeolithic-type diet on characteristics of the metabolic syndrome: a randomized controlled pilot-study.Lipids in health and disease · 2014Trial
- Long-term effects of a Palaeolithic-type diet in obese postmenopausal women: a 2-year randomized trial.European journal of clinical nutrition · 2014Trial
- Beneficial effects of a Paleolithic diet on cardiovascular risk factors in type 2 diabetes: a randomized cross-over pilot study.Cardiovascular diabetology · 2009Trial
- Effects of the Paleo diet on resting metabolic rate in handball players.Scientific reports · 2026Article
- The Effect of an Autoimmune Protocol (AIP) Diet in Adults With Rheumatoid Arthritis: A Single Arm Crossover Pilot Feasibility Study.Musculoskeletal care · 2026Article
- Association between Paleolithic diet fraction and systemic low-grade chronic inflammation in the Malmö diet and cancer study cohort.European journal of nutrition · 2025Article
- Impact of Paleo Diet on Body Composition, Carbohydrate and Fat Metabolism of Professional Handball Players.Nutrients · 2023Article
- Review
- Palaeolithic diet score and risk of breast cancer among postmenopausal women overall and by hormone receptor and histologic subtypes.European journal of clinical nutrition · 2023Article
- The Paleolithic Diet.Cureus · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesPrevention of cardiovascular diseases by paleolithic or hunter-gatherer diets has been discussed during recent years.
methodsOur aim was to assess the effect of a paleolithic diet in a pilot study on healthy volunteers during 3 weeks. The intention was to include 20 subjects, of whom 14 fulfilled the study. Complete dietary assessment was available for six subjects.
resultsMean weight decreased by 2.3 kg (P<0.001), body mass index by 0.8 (P<0.001), waist circumference by 0.5 cm (P=0.001), systolic blood pressure by 3 mm Hg (P=0.03) and plasminogen activator inhibitor-1 by 72% (P=0.020). Regarding nutrient intake, intake of energy decreased by 36%, and other effects were also observed, both favourable (fat composition, antioxidants, potassium-sodium rate) and unfavourable (calcium).
conclusionThis short-term intervention showed some favourable effects by the diet, but further studies, including control group, are needed.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.