Interferon: the magic bullet to prevent hepatocellular carcinoma recurrence after resection?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Who cites it

13 citing papers in PubMed.

1. Hepatocellular Carcinoma: Surgical Management and Evolving Therapies.Cancer treatment and research · 2024
   Review
2. IFN-α facilitates the effect of sorafenib via shifting the M2-like polarization of TAM in hepatocellular carcinoma.American journal of translational research · 2021
   Article
3. Dihydropyrimidine dehydrogenase predicts survival and response to interferon-α in hepatocellular carcinoma.Cell death & disease · 2018
   Article
4. Extracellular 2'5'-oligoadenylate synthetase 2 mediates T-cell receptor CD3-ζ chain down-regulation via caspase-3 activation in oral cancer.Immunology · 2016
   Article
5. Antitumor potential of a synthetic interferon-alpha/PLGF-2 positive charge peptide hybrid molecule in pancreatic cancer cells.Scientific reports · 2015
   Article
6. Adjuvant interferon for early or late recurrence of hepatocellular carcinoma and mortality from hepatocellular carcinoma following curative treatment: A meta-analysis with comparison of different types of hepatitis.Molecular and clinical oncology · 2014
   Article
7. Systemic therapy of hepatocellular carcinoma: current status and future perspectives.World journal of gastroenterology · 2014
   Review
8. Development of a miR-26 companion diagnostic test for adjuvant interferon-alpha therapy in hepatocellular carcinoma.International journal of biological sciences · 2013
   Article
9. Up-regulation of platelet-derived growth factor-A is responsible for the failure of re-initiated interferon alpha treatment in hepatocellular carcinoma.BMC cancer · 2012
   Article
10. Treatment Response After Unusual Low Dose Sorafenib: Diagnosis with Perfusion CT and Follow-up in a Patient with Recurrent Hepatocellular Carcinoma.Journal of gastrointestinal cancer · 2012
    Article
11. Interferon-γ induces autophagy with growth inhibition and cell death in human hepatocellular carcinoma (HCC) cells through interferon-regulatory factor-1 (IRF-1).Cancer letters · 2012
    Article
12. MicroRNA expression, survival, and response to interferon in liver cancer.The New England journal of medicine · 2009
    Article
13. Surgical treatment for hepatocellular carcinoma in cirrhotic patients. Guide to the selection and decision-making process in a context of multimodal strategy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2009
    Review

Corrections and comments

• Commented on by
  Re: Interferon: the magic bullet to prevent hepatocellular carcinoma recurrence after resection?2008
• Comment on
  A randomized, controlled trial of postoperative adjuvant interferon therapy after resection of hepatocellular carcinoma.2007

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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