Evidence map›Paper›PMID 17522276›Full record

ArticleJournal of clinical microbiology2007

RTX toxin actin cross-linking activity in clinical and environmental isolates of Vibrio cholerae.

Christina L Cordero, Shanmuga Sozhamannan, Karla J Fullner Satchell

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.8field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Proteomic Analysis of the Fish PathogenAnimals : an open access journal from MDPI · 2024
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  4. Review
  5. Article
  6. Article
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  9. Connecting actin monomers by iso-peptide bond is a toxicity mechanism of the Vibrio cholerae MARTX toxin.Proceedings of the National Academy of Sciences of the United States of America · 2008
    Article
  10. Article
  11. Article
  12. Article
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  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Christina L CorderoDepartment of Microbiology-Immunology, Feinberg School of Medicine, Northwestern University, 303 E. Chicago Ave., Tarry 3-713, Chicago, IL 60611, USA.
Shanmuga Sozhamannan
Karla J Fullner Satchell
Northwestern University · USNaval Medical Research Command · US

Funding

Genetic and biochemical study ov V. cholerase RTX toxinR01AI051490 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SATCHELL, KARLA J F · 2003 to 2012
$3.3M
Minority Predoctoral Fellowship ProgramF31AI052490 · NIAID · NORTHWESTERN UNIVERSITY · PI CORDERO, CHRISTINA L · 2002 to 2005
$107k
NIAID NIH HHS AI051490NIAID NIH HHS F31 AI052490NIAID NIH HHS F31-AI52490NIAID NIH HHS R01 AI051490
6 · The paper itself

Abstract

Vibrio cholerae strains from diverse O-antigen groups were evaluated for RTX toxin actin cross-linking activity. This study demonstrates that the actin cross-linking domain sequence is present within rtxA in the majority of clinical and environmental isolates tested, and the RTX toxin produced by these strains catalyzes the covalent cross-linking of cellular actin.

Indexed as

ActinsAntigens, BacterialBacterial ToxinsCholeraEnvironmentHumansVibrio choleraeActinsAntigens, BacterialBacterial Toxins

Identifiers

PMID17522276
PMCPMC1932970
OpenAlexW2021473893

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.