Trial reportLearning & memory (Cold Spring Harbor, N.Y.)2007
Reconsolidation of declarative memory in humans.
Trial report in Learning & memory (Cold Spring Harbor, N.Y.), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
64 citing papers in PubMed, 229 citations in OpenAlex.
- Repeated labilization-reconsolidation processes strengthen declarative memory in humans.PloS one · 2011Trial
- Trial
- Condition-specific neural signatures of reactivation during post-retrieval rest: An EEG study.iScience · 2026Article
- Prefrontal Cortex Responses to Conflicting Information.Human brain mapping · 2025Article
- Memory updating and the structure of event representations.Trends in cognitive sciences · 2025Review
- Reactivation fails to offer the improvement sleep does.Sleep advances : a journal of the Sleep Research Society · 2025Article
- New Approaches to Addiction Treatment Based on Learning and Memory.Current topics in behavioral neurosciences · 2025Review
- A working memory dependent dual process model of the testing effect.NPJ science of learning · 2024Review
- Temporal dynamics of trauma memory persistence.Journal of the Royal Society, Interface · 2023Article
- Toward personalized circuit-based closed-loop brain-interventions in psychiatry: using symptom provocation to extract EEG-markers of brain circuit activity.Frontiers in neural circuits · 2023Review
- Odor cueing during sleep improves consolidation of a history lesson in a school setting.Scientific reports · 2022Article
- Can we learn from errors? Retrieval facilitates the correction of false memories for pragmatic inferences.PloS one · 2022Article
- Article
- Symptom provocation for treatment of obsessive-compulsive disorder using transcranial magnetic stimulation: A step-by-step guide for professional training.Frontiers in psychiatry · 2022Article
- Episodic memory enhancement versus impairment is determined by contextual similarity across events.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Post-retrieval Distortions of Self-Referential Negative Memory: Valence Consistency Enhances Gist-Directed False, While Non-negative Interference Generates More Intrusive Updates.Frontiers in psychology · 2021Article
- The Intersection of Offline Learning and Rehabilitation.Frontiers in human neuroscience · 2021Article
- Reactivation during sleep with incomplete reminder cues rather than complete ones stabilizes long-term memory in humans.Communications biology · 2020Article
- Article
- Neural Overlap in Item Representations Across Episodes Impairs Context Memory.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The reconsolidation hypothesis states that a consolidated memory could again become unstable and susceptible to facilitation or impairment for a discrete period of time after a reminder presentation. The phenomenon has been demonstrated in very diverse species and types of memory, including the human procedural memory of a motor skill task but not the human declarative one. Here we provide evidence for both consolidation and reconsolidation in a paired-associate learning (i.e., learning an association between a cue syllable and the respective response syllable). Subjects were given two training sessions with a 24-h interval on distinct verbal material, and afterward, they received at testing two successive retrievals corresponding to the first and second learning, respectively. Two main results are noted. First, the first acquired memory was impaired when a reminder was presented 5 min before the second training (reconsolidation), and also when the second training was given 5 min instead of 24 h after the first one (consolidation). Second, the first retrieval proved to influence negatively on the later one (the retrieval-induced forgetting [RIF] effect), and we used the absence of this RIF effect as a very indicator of the target memory impairment. We consider the demonstration of reconsolidation in human declarative memory as backing the universality of this phenomenon and having potential clinical relevance. On the other hand, we discuss the possibility of using the human declarative memory as a model to address several key topics of the reconsolidation hypothesis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.