ArticleAnnals of epidemiology2007
Diet during pregnancy and risk of preeclampsia or gestational hypertension.
Article in Annals of epidemiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02706158 (Testing the Effect of a Dietary Intervention Program on the Incidence of Pre-eclampsia in Women at Risk), which is not on this map. Cited by 78 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Testing the Effect of a Dietary Intervention Program on the Incidence of Pre-eclampsia in Women at Risk
Who cites it
78 citing papers in PubMed, 7 syntheses or guidelines pooled it, 172 citations in OpenAlex.
- Effects of maternal folate and vitamin B12 on gestational diabetes mellitus: a dose-response meta-analysis of observational studies.European journal of clinical nutrition · 2022Pooled it
- Maternal Dietary Patterns and Pregnancy Hypertension in Low- and Middle-Income Countries: A Systematic Review and Meta-analysis.Advances in nutrition (Bethesda, Md.) · 2021Pooled it
- Pooled it
- Periconceptional folic acid fortification for the risk of gestational hypertension and pre-eclampsia: a meta-analysis of prospective studies.Maternal & child nutrition · 2016Pooled it
- Clinical risk factors for pre-eclampsia determined in early pregnancy: systematic review and meta-analysis of large cohort studies.BMJ (Clinical research ed.) · 2016Pooled it
- The association between dietary factors and gestational hypertension and pre-eclampsia: a systematic review and meta-analysis of observational studies.BMC medicine · 2014Pooled it
- Vitamin D during pregnancy and maternal, neonatal and infant health outcomes: a systematic review and meta-analysis.Paediatric and perinatal epidemiology · 2012Pooled it
- Assessment of dietary fish consumption in pregnancy: comparing one-, four- and thirty-six-item questionnaires.Public health nutrition · 2014Trial
- Proportions and concentrations of serum n-3 fatty acids can be increased by dietary counseling during pregnancy.European journal of clinical nutrition · 2013Trial
- A pilot randomized controlled trial to promote healthful fish consumption during pregnancy: the Food for Thought Study.Nutrition journal · 2013Trial
- Differences in Dietary-Related Experiences, Determinants, and Information-Seeking Behaviors Among Pregnant and Postpartum Women: Cross-Sectional Survey Study.JMIR formative research · 2026Article
- Association of the maternal fish and PUFA intake with the risk of hypertensive disorders of pregnancy: a nationwide birth cohort-The Japan Environment and Children's Study (JECS).European journal of nutrition · 2026Article
- Calcium and zinc status and risk of preeclampsia in pregnant women with varying seafood intake in Ambon City: a case-control study.BMC research notes · 2026Observational
- Dietary Intake and Eating Behavior During Pregnancy by Pre-Pregnancy Nutritional Status.Life (Basel, Switzerland) · 2026Article
- The impact of folic acid supplementation in early to mid-pregnancy on the risk of hypertensive disorders of pregnancy: the Japan environment and children's study.BMC pregnancy and childbirth · 2026Article
- Assessing rates of dietary counseling in obstetric patients with hypertensive disorders of pregnancy and related conditions.Pregnancy hypertension · 2025Article
- Associations between food frequency checklist responses and internal biomarkers of exposure to pesticides and heavy metals among U.S. pregnant women.Next research · 2025Article
- Lifetime history of hypertensive disorders of pregnancy is associated with shorter sleep duration and more sleep disturbance in midlife: results from the Project Viva women's health cohort.Biology of sex differences · 2025Article
- Fatty acid signatures in people with HIV: association with adverse pregnancy outcomes and offspring anthropometrics.Journal of acquired immune deficiency syndromes (1999) · 2025Article
- A Review of Dietary and Lifestyle Management of Pre-Eclampsia and Postpartum Eclampsia.Preventive nutrition and food science · 2025Review
18 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
purposeWe sought to examine associations of first-trimester intake of calcium, n-3 and n-6 fatty acids, trans fatty acids, magnesium, folate, and vitamins C, D, and E with preeclampsia (PE) and gestational hypertension (GH).
methodsWe studied associations of diet with PE or GH among 1718 women in the prospective cohort study Project Viva, using logistic regression and adjusting for maternal age, prepregnancy body mass index, first trimester systolic blood pressure, race/ethnicity, education, and parity. We assessed first-trimester diet using a validated semiquantitative food frequency questionnaire.
resultsA total of 59 (3%) women developed PE, and 119 developed (7%) GH. We found a somewhat-lower risk of PE associated with higher intake of the elongated n-3 fatty acids docosahexaenoic and eicosapentaenoic acids (odds ratio [OR] 0.84, 95% confidence interval [95% CI]: 0.69-1.03 per 100 mg/day), fish (OR 0.91, 95% CI 0.75-1.09 per serving/day), and the ratio of docosahexaenoic + eicosapentaenoic to arachadonic acid (OR 0.82, 95% CI 0.66-1.01). We did not observe a lower risk of GH or PE with a greater intake of calcium; vitamin C, D, or E; milk; magnesium; folate; or with lower intake of n-6 or trans fatty acids.
conclusionsOur results support a potential benefit for elongated n-3 fatty acids in preventing preeclampsia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.