ArticleNeuron2007
NRG1 and synaptic function in the CNS.
Article in Neuron, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- Associations between cerebrospinal fluid markers and cognition in ageing and dementia: A systematic review.The European journal of neuroscience · 2022Pooled it
- Gene set enrichment analysis and protein-protein interaction network analysis after sciatic nerve injury.Annals of translational medicine · 2020Article
- Neuregulin directed molecular mechanisms of visual cortical plasticity.The Journal of comparative neurology · 2019Review
- Axonal and Schwann cell BACE1 is equally required for remyelination of peripheral nerves.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015Article
- Resequencing and association analysis of PTPRA, a possible susceptibility gene for schizophrenia and autism spectrum disorders.PloS one · 2014Article
- Gestational hypoxia induces sex-differential methylation of Crhr1 linked to anxiety-like behavior.Molecular neurobiology · 2013Article
- Sustained high levels of neuregulin-1 in the longest-lived rodents; a key determinant of rodent longevity.Aging cell · 2012Article
- Monosynaptic inputs to ErbB4-expressing inhibitory neurons in mouse primary somatosensory cortex.The Journal of comparative neurology · 2011Article
- Loss of function studies in mice and genetic association link receptor protein tyrosine phosphatase α to schizophrenia.Biological psychiatry · 2011Article
- Neuregulin 1-erbB4 pathway in schizophrenia: From genes to an interactome.Brain research bulletin · 2010Review
- Constraint-induced movement therapy in the adult rat after unilateral corticospinal tract injury.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2008Article
- Neuregulin 1 in neural development, synaptic plasticity and schizophrenia.Nature reviews. Neuroscience · 2008Review
- Alteration of BACE1-dependent NRG1/ErbB4 signaling and schizophrenia-like phenotypes in BACE1-null mice.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent genetic evidence indicates that neuregulin 1 (NRG1) and its receptor erbB4 may be susceptibility genes in schizophrenia, but their function in CNS synaptic transmission and circuitry is not well understood. In this issue of Neuron, studies from Li et al. and Woo et al. show that NRG1 and erbB4 regulate transmission at brain glutamate and GABA synapses. These findings raise the possibility of synaptic defects in schizophrenia.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.