Evidence map›Paper›PMID 17520274›Full record

ReviewPflugers Archiv : European journal of physiology2007

Regulation of the actin cytoskeleton by phosphatidylinositol 4-phosphate 5 kinases.

Yuntao S Mao, Helen L Yin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pflugers Archiv : European journal of physiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 77 citations in OpenAlex.

  1. Emerging oralFrontiers in oral health · 2025
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  4. Fucoidan (Marine drugs · 2022
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  7. Review
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  14. Review
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  16. Phosphatidylinositol 4,5-bisphosphate regulates CapZβ1 and actin dynamics in response to mechanical strain.American journal of physiology. Heart and circulatory physiology · 2013
    Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yuntao S MaoDepartment of Physiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX, 75390-9040, USA.
Helen L Yin
The University of Texas Southwestern Medical Center · US

Funding

SIGNAL REGULATION OF CARDIAC CYTOKINE SYNTHESIS AND MECHANICAL FUNCTIONP50GM021681 · NIGMS · UT SOUTHWESTERN MEDICAL CENTER · PI NWARIAKU, FIEMU E. · 1985 to 2009
$12.8M
NIGMS NIH HHS NIH P05GM21681NIGMS NIH HHS NIH R01GM06110
6 · The paper itself

Abstract

Phosphatidylinositol (4,5)-bisphosphate (PIP(2)) is an important lipid mediator that has multiple regulatory functions. There is now increasing evidence that the phosphatidylinositol 4-phosphate 5 kinases (PIP5Ks), which synthesize PIP(2), are regulated spatially and temporally and that they have isoform-specific functions and regulations. This review will summarize the highlights of recent developments in understanding how the three major PIP5K isoforms regulate the actin cytoskeleton and other important cellular processes.

Indexed as

1-Phosphatidylinositol 4-KinaseActinsAnimalsCytoskeletonHumansIsoenzymesMicrofilament ProteinsPhosphatidylinositol 4,5-Diphosphate1-Phosphatidylinositol 4-KinaseActinsIsoenzymesMicrofilament ProteinsPhosphatidylinositol 4,5-Diphosphate

Identifiers

PMID17520274
OpenAlexW2072530403

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.