Evidence map›Paper›PMID 17520234›Full record

ReviewDer Nervenarzt2007

[Early evaluation of neurological prognosis and therapy after cardiopulmonary resuscitation: current opportunities and clinical implications].

A Ragoschke-Schumm, R Pfeifer, G Marx, N Knoepffler, O W Witte, S Isenmann

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Der Nervenarzt, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A Ragoschke-SchummInstitut für Diagnostische und Interventionelle Radiologie, Jena, Germany.
R Pfeifer
G Marx
N Knoepffler
O W Witte
S Isenmann

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The developments of cardiopulmonary resuscitation and intensive care medicine have made possible survival after cardiac arrest. However, only 10-30% of patients with initially successful resuscitation later reach a state without severe neurological impairment. Ethical and socioeconomic reasons therefore make early prognosis important for certain patients. There are no reliable parameters for predictions of good clinical outcome. If clinical information is consistent with severe hypoxic brain damage, cortical somatosensory evoked potentials are absent, and neuron-specific enolase values exceed 33-65 microg/l, recovery of consciousness can be excluded. The same result can be predicted if brain imaging shows severe hypoxemic changes or if a myoclonic status occurs on the first day. In summary, the prognosis in patients with cerebral anoxy and cardiopulmonary resuscitation remains poor. Treatment with hypothermia for 24 h is recommended.

Indexed as

Neurologic ExaminationBiomarkersBrainBrain Damage, ChronicEarly DiagnosisElectroencephalographyEthics, MedicalEvoked Potentials, SomatosensoryHeart ArrestHumansHypoxia, BrainMagnetic Resonance ImagingPersistent Vegetative StatePhosphopyruvate HydratasePrognosisResuscitation OrdersBiomarkersPhosphopyruvate Hydratase

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.